Results 51 to 60 of about 56,471 (208)
El marco europeo de la política de enfermedades raras [PDF]
, 2010 Comunicación presentada en el Curso "Marco actual y el impacto social de las enfermedades raras en España", dentro de los Cursos de verano UBU ...
Montserrat Moliner, Antoni
core
Hydroxytyrosol targets extracellular matrix remodeling by endothelial cells and inhibits both ex vivo and in vivo angiogenesis [PDF]
, 2016 This is the preprint version of our manuscript, corresponding to the article that has been published in final form at FOOD CHEMISTRY with DOI: 10.1016/j.foodchem.2016.10.111The health benefits of olive oil are attributed to their bioactive compounds ...
García-Vilas, Javier A. +2 more
core +1 more source
Los registros de enfermedades en la investigación epidemiológica de las enfermedades raras en España
Revista Española de Salud Pública, 2006 Fundamento: En el caso de las enfermedades raras existen dificultades para utilizar herramientas como los registros de enfermedades. El objetivo de este trabajo es describir la situación de los registros sobre enfermedades raras en España.
Óscar Zurriaga Lloréns +10 more
doaj
Suicide gene therapy targeting ewing sarcoma via an ewing-specific GGAA promoter
Scientific ReportsWe recently demonstrated that GGAA promoters (GGAAprom) can be used to drive the expression of therapeutic genes (i.e., Cas9) in vitro and in vivo in a highly specific way in Ewing sarcoma cells.
Saint T. Cervera +4 more
doaj +1 more source
Chitin-challenged Mice Model to Study M2 Macrophages Polarization
Bio-Protocol, 2015 Chitin is a key component of insects, fungi, and house-dust mites. Chitin has been shown to induce M2-type immune responses in vivo. Intranasal or intraperitoneal (i.p.) administration of chitin particles results in infiltration of eosinophils to the ...
Lidia Jiménez-García +3 more
doaj +1 more source
Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease
Epilepsia, EarlyView.Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa +17 more
wiley +1 more source
Revista Española de Discapacidad, 2013 Bañón Hernández, A.M. y Fornieles Alcaraz, J. (2013): “Internacionalización, formación y análisis de la realidad. Tres conceptos esenciales en el desarrollo de acciones positivas por parte de FEDER (Federación Española de Enfermedades Raras)”.
Antonio M. Bañón Hernández +1 more
doaj
Evaluation of the anti-angiogenic potential of hydroxytyrosol derivatives [PDF]
, 2018 Angiogenesis, a process which allows the formation of new vessels from pre-existing ones, is an essential phenomenon for tumor survival since it allows cancer cells to obtain nutrients and oxygen.
Carrillo Fernández, Paloma +7 more
core
Trabajar para pacientes con enfermedades raras, de baja prevalencia y complejas: share, care, cure [PDF]
, 2017 El ISBN corresponde a la versión electrónica del documentoCada año, se diagnostica una enfermedad rara a medio millón de europeos. Ningún país puede afrontar este reto en solitario.
Comisión Europea. Dirección General de Salud y Seguridad Alimentaria
core +1 more source
The FEBS Journal, EarlyView.Calcium‐binding S100 proteins are important mediators of inflammation in humans. Distant members of this family have been recently discovered in teleost fish but their resemblance to human proteins has not been explored yet. This study demonstrates that zebrafish‐specific S100i1 and S100i2 (ictacalcins) possess identical structural organization and ...
Liz Hernández +13 more
wiley +1 more source