The splicing factor ASF/SF2 and intron retention as markers of endothelial senescence
Frontiers in Physiology, 2012 Aging is the major risk factor per se for the development of cardiovascular diseases. The senescence of endothelial cells, that line the lumen of blood vessels, is at the cellular basis of these age-dependent vascular pathologies, including ...
Francisco Javier Blanco +1 more
doaj +1 more source
[Genetic protocol in primary care for rare diseases: Wolfram syndrome as a prototype]. [PDF]
Aten Primaria, 2022 Esteban-Bueno G +4 more
europepmc +1 more source
Development of text mining tools for information retrieval from patents [PDF]
, 2017 Biomedical literature is composed of an ever increasing number of publications in natural language. Patents are a relevant fraction of those, being important sources of information due to all the curated data from the granting process.
A Faro +7 more
core +1 more source
Cuando el cáncer es una enfermedad rara
Arbor: Ciencia, Pensamiento y Cultura, 2018 Heredar una alteración en un gen de susceptibilidad al cáncer supone vivir con una probabilidad alta de desarrollar la enfermedad, con frecuencia más de una vez, y por lo general a una edad temprana. Y también convivir con otros familiares, padres, hijos,
Miguel Urioste, Javier Benítez
doaj +1 more source
Fasentin, a glucose uptake inhibitor, is also able to inhibit angiogenesis [PDF]
, 2017 Es comunicación a congreso en formato pósterThe role of glucose on endothelial cell (EC) metabolism and angiogenesis has been an emerging issue in the last few years.
Carrillo, Paloma +4 more
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Endoglin-mediated angiogenic responses are regulated by its cytosolic domain [PDF]
, 2015 1 p.This work was supported by grants from Czech Science foundation GACR number 15-24015S, the Grant Agency of Charles University in Prague (1284214/C and 1158413/C), Charles University in Prague (SVV/2014/260064), European Regional Development Fund ...
Bernabéu, Carmelo +6 more
core +1 more source
Acidemia propiónica. Una enfermedad genética rara
Revista de Ciencias Médicas de Pinar del Río, 2018 La acidemia propiónica, aunque rara, es uno de los errores del metabolismo más frecuentes, un caso por cada 100,000 nacidos vivos. Tiene herencia autosómica recesiva. Se presenta un caso con diagnóstico de acidemia propiónica. Se realizó una revisión de 12 citas bibliográficas en base de datos Pubmed, OMIM, la misma se fundamentó en las características
Deysi Licourt Otero +3 more
openaire +2 more sources
A role for antizyme inhibitor 2 in the biosynthesis and content of serotonin and histamine in mouse mast cells [PDF]
, 2015 Polyamines (putrescine, spermidine and spermine; PAs) are essential for the majority of living cells. Antizymes and antizyme inhibitors are key regulatory proteins of PA levels by affecting ornithine decarboxylase and PA uptake.
Acosta-Andrade, Carlos +5 more
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Enfermedades raras del corazón [PDF]
Revista Colombiana de Cardiología, 2022 openaire +1 more source
Antitumor and antiangiogenic potential of solomonamide synthesis intermediates [PDF]
, 2017 Es comunicación (formato panel) a congreso internacionalIn this work we developed a new synthetic strategy towards the solomonamides. a novel class of cyclopeptides of marine origin. The described synthetic approach utilized an olefin metathesis reaction
Carrillo Fernandez, Paloma +6 more
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