Results 131 to 140 of about 3,800,912 (336)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
BMC Health Services ResearchBackground Transvaginal mesh (TVM) surgeries emerged as an innovative treatment for stress urine incontinency and/or pelvic organ prolapse in 1996. Years after rapid adoption of these surgeries into practice, they are a key example of worldwide failure ...
Mina Motamedi +2 more
doaj +1 more source
Playful Civic Learning: Enabling Lateral Trust and Reflection in Game-based Public Participation
International Journal of Communication, 2014 Attempts to improve participation in civic life often focus on increasing the number of citizens engaged rather than improving the quality of engagement. As digital interventions flood the civic space, investigating the mediating interfaces that provide
Eric Gordon, Jessica Baldwin-Philippi
doaj +2 more sources
Community engagement: managers’ viewpoints [PDF]
, 2011 Managers are invaluable for their support of fieldwork placement for social work students. This chapter examines factors that influence managers’ decision-making towards student placement provision, a role which has traditionally been overlooked in the ...
Hanlen, Patricia
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Patient engagement at the heart of all European Society of Cardiology activities [PDF]
, 2019 Donna Fitzsimons
openalex +1 more source
Leadership and employee engagement in the New Zealand dairy farming industry - is there a link with milk production performance? : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University, Manawatu, New Zealand [PDF]
, 2017 This study sought to investigate which leadership styles were more effective at increasing employee engagement and/or overall milk production performance in the context of the New Zealand (NZ) dairy farming industry. This study also sought to investigate
Rolfe, Christina
core
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Methods in PsychologyDistance learning was a unique struggle for teachers, who reported some of the highest levels of stress among any professionals in the U.S. This study investigates teachers' emotional experience and creative development in COVID-19 pandemic distance ...
Ross C. Anderson, Mari Livie
doaj +1 more source