Results 51 to 60 of about 738,621 (291)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

A review of recent advances in the application of machine learning algorithms for gas turbine combustion

Propulsion and Energy
With the rapid advancement of computing power and significant progress in machine learning (ML) algorithms, ML has shown immense potential across a wide range of fields, particularly in simulation, experimental analysis, and condition monitoring.
Da Mo, Yuzhen Lin, Yixiong Liu, Yuchen Wang, Ziyu Qin, Xiao Han   +5 more
doaj   +1 more source

Effect of Diesel Fuel-Coconut Oil-Butanol Blends on Operational Parameters of Diesel Engine

Energies, 2020
The global concentration of greenhouse gasses in the atmosphere is increasing as well as the emissions of harmful pollutants. Utilization of liquid biofuels in combustion engines helps to reduce these negative effects. For diesel engines, the most common
Jakub Čedík, Martin Pexa, Michal Holúbek, Zdeněk Aleš, Radek Pražan, Peter Kuchar   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Sub-series 2: Publications

, 1986
Newsletter discussing updates, news, and events for the Model Engine Collectors' Association as well as topics of interest to ...
Model Engine Collectors' Association
core   +1 more source

Acoustic mode detection in an engine nacelle with a scaled rig fan

Advances in Aerodynamics
Acquiring acoustic modes with high quality data in large-scale nacelles is quite challenging in the engine industry because of the complex configuration, high flow speed, tremendous number of acoustic modes, and some other extraordinary interference.
Kangle Xu, Yiang Lyu, Lijuan Feng, Changchun Liu, Jiayuan Ji   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The acoustics of racing engine intake systems [PDF]

, 2004
Naturally aspirated racing engines have tuned intake systems and can now achieve volumetric efficiencies in excess of 125% and peak engine speeds in excess of 18,000 rev/min.
Harrison, M. F., Dunkley, A.
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source