Results 71 to 80 of about 2,795,262 (398)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Jay Carter Enterprises, Incorporated steam engine [PDF]

, 1981
The Small Community Solar Thermal Power Experiment (SCSE) selected an organic rankine cycle (ORC) engine driving a high speed permanent magnet alternator (PMA) as the baseline power conversion subsystem (PCS) design.

core   +1 more source

Acoustic mode detection in an engine nacelle with a scaled rig fan

Advances in Aerodynamics
Acquiring acoustic modes with high quality data in large-scale nacelles is quite challenging in the engine industry because of the complex configuration, high flow speed, tremendous number of acoustic modes, and some other extraordinary interference.
Kangle Xu, Yiang Lyu, Lijuan Feng, Changchun Liu, Jiayuan Ji   +4 more
doaj   +1 more source

Design method and the development of the low-temperature-difference indirect heating Stirling engine

Nihon Kikai Gakkai ronbunshu, 2018
Low-temperature-difference indirect heating Stirling engine is the most suitable device for a small-scale wood biomass combined heat and power. To design this type of Stirling engine, conventional design method is not sufficient for optimizing working ...
Makoto TAKEUCHI, Shinji SUZUKI, Yutaka ABE   +2 more
doaj   +1 more source

Spin Heat Engine Coupled to a Harmonic-Oscillator Flywheel. [PDF]

Physical Review Letters, 2018
We realize a heat engine using a single-electron spin as a working medium. The spin pertains to the valence electron of a trapped ^{40}Ca^{+} ion, and heat reservoirs are emulated by controlling the spin polarization via optical pumping.
D. Lindenfels, Oliver Grab, C. Schmiegelow, V. Kaushal, J. Schulz, Ferdinand Schmidt-Kaler, U. Poschinger   +6 more
semanticscholar   +1 more source

Mindful Engineers in Sustainable Engineering

IEEE Technology and Society Magazine, 2019
According to the Encyclopadia Britannica, the establishment of the Royal Society of London for Improving Natural Knowledge (Royal Society), the "oldest national scientific society in the world," was on November 28, 1660. In 1818, the Institution of Civil Engineers (ICE), the first professional engineering body, was also set up in London.
Basart i Muñoz, Josep M., Farrús, Mireia, Serra, Montse   +2 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Rocket engine analog simulation [PDF]

, 1968
Mathematical equations simulate the operation of a rocket engine, simulate destructive and nondestructive tests to verify engine design feasibility, and investigate nonlinear variations in engine ...
Philyaw, B. K., Randazzo, G. J.
core   +1 more source

Implementation of the LandTrendr Algorithm on Google Earth Engine

Remote Sensing, 2018
The LandTrendr (LT) algorithm has been used widely for analysis of change in Landsat spectral time series data, but requires significant pre-processing, data management, and computational resources, and is only accessible to the community in a ...
R. Kennedy, Zhiqiang Yang, N. Gorelick, J. Braaten, Lucas Cavalcante, W. Cohen, S. Healey   +6 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source