Results 61 to 70 of about 11,940,761 (361)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Reduced integral scheme of damaged divided back stress elasto plastic model based on full implicit algorithm

open access: yesNihon Kikai Gakkai ronbunshu, 2015
The purpose of this study is formulating the reduced integration method of damage elasto plastic constitutive model with divided back stress based on full implicit framework.
Shogo SANNOMARU   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Current status and prospects of aviation remanufacturing technology based on cold spray

open access: yesHangkong gongcheng jinzhan
Cold spray additive manufacturing technology,with its unique "solid-state deposition" process characteristics,has shown great application potential in the repair and remanufacturing of damaged aerospace structures.
CHI Yada   +4 more
doaj   +1 more source

Investigation of cylinder deactivation and variable valve actuation on gasoline engine performance [PDF]

open access: yes, 2014
Increasingly stringent regulations on gasoline engine fuel consumption and exhaust emissions require additional technology integration such as Cylinder Deactivation (CDA) and Variable valve actuation (VVA) to improve part load engine efficiency.
Kuruppu, C, Pesiridis, A, Rajoo, S
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Acute dermal toxicity study of new, used and laboratory aged aircraft engine oils

open access: yesToxicology Reports, 2019
There is little data available on toxicity levels of used aircraft engine oils relative to their unused (new) versions. This study was conducted to determine if new engine oils and their used versions have the potential to induce dermal irritation ...
Isaie Sibomana   +4 more
doaj   +1 more source

Performance metrics in engineering change management - Key Performance Indicators and engineering change performance levels

open access: yes2016 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM), 2016
A key aspect of engineering change management is the efficient handling of engineering changes within the product development process. Thus, performance measurement criteria, i.e. performance metrics or Key Performance Indicators, are often used in a variety of domains to either reveal performance deficit or improve a certain process.
N. Kattner, T. Wang, U. Lindemann
openaire   +2 more sources

A new internal combustion engine configuration: opposed pistons with crank offset [PDF]

open access: yes, 2007
[Abstract]: Theoretical and experimental performance results for a new internal combustion engine configuration are presented in this paper. The engine is a piston ported, spark ignition petrol engine which consists of two opposed pistons in a single ...
Buttsworth, David R., Malpress, Ray
core   +1 more source

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