Results 81 to 90 of about 957,254 (314)
Computer simulation of engine systems [PDF]
The use of computerized simulations of the steady state and transient performance of jet engines throughout the flight regime is discussed. In addition, installation effects on thrust and specific fuel consumption is accounted for as well as engine ...
Fishbach, L. H.
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Strain gage system evaluation program [PDF]
A program was conducted to determine the reliability of various strain gage systems when applied to rotating compressor blades in an aircraft gas turbine engine.
Dolleris, G. W. +2 more
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Microbial Cell Factories, 2020 Background Dewatering constitutes a major challenge to the production of microalgae, accounting for 20–30% of the product cost. This presents a setback for the applicability of microalgae in the development of several sustainable products.
Mutah Musa +5 more
doaj +1 more source
Reliability analysis of forty-five strain-gage systems mounted on the first fan stage of a YF-100 engine [PDF]
The reliability of 45 state-of-the-art strain gage systems under full scale engine testing was investigated. The flame spray process was used to install 23 systems on the first fan rotor of a YF-100 engine; the others were epoxy cemented.
Frause, L. M., Holanda, R.
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Self-oscillations in an Alpha Stirling Engine: a bifurcation analysis
, 2019 We study a thermo-mechanical system comprised of an alpha Stirling engine and a flywheel from the perspective of dynamical systems theory. Thermodynamics establish a static relation between the flywheel's angle and the forces exerted by the two power ...
Castanos, Fernando, Gromov, Dmitry
core
The Signal Data Explorer: A high performance Grid based signal search tool for use in distributed diagnostic applications [PDF]
, 2006 We describe a high performance Grid based signal search tool for distributed diagnostic applications developed in conjunction with Rolls-Royce plc for civil aero engine condition monitoring applications.
Austin, Jim +4 more
core +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source