Results 81 to 90 of about 25,670,789 (354)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Smart Search Engine For Information Retrieval [PDF]

open access: yes, 2009
This project addresses the main research problem in information retrieval and semantic search. It proposes the smart search theory as new theory based on hypothesis that semantic meanings of a document can be described by a set of keywords.
SUN, LEILEI
core  

A comprehensive aerodynamic-thermal-mechanical design method for fast response turbocharger applied in aviation piston engines

open access: yesPropulsion and Power Research
Limited by the poor transient response performance of turbochargers, the dynamic performance of aviation piston engines tends to deteriorate. In a bid to enhance the turbocharger's acceleration capabilities, this study scrutinizes various factors ...
Yu Zhou   +7 more
doaj   +1 more source

Effects of injection pressure and impingement distance on flat-wall impinging spray flame and its heat flux under diesel engine-like condition

open access: yesAdvances in Mechanical Engineering, 2019
Heat loss is one of the main causes of energy losses in modern direct injection diesel engines. This heat loss of the engine occurs during combustion, mainly due to the heat transfer between the impinging spray flame and the piston cavity wall.
Rizal Mahmud   +5 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

PROSPECTS OF DEVELOPMENT ELECTRONIC AUTOMATIC CONTROL SYSTEMS FOR GAS-TURBINE ENGINES

open access: yesАвіаційно-космічна техніка та технологія, 2018
The analysis of the basic directions of electronic automatic control systems for aviation gas-turbine engines (FADEC) development is presented. This analysis is executed on the base of materials of the Scientific and Technical Congress of Aero-Engine ...
Геннадий Степанович Ранченко   +1 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Computational and experimental study of air hybrid engine concepts [PDF]

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityThe air hybrid engine absorbs the vehicle kinetic energy during braking, stores it in an air tank in the form of compressed air, and reuses it to start the ...
Lee, Cho-Yu
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Experimental Study of Evaporation Characteristics of Acoustically Levitated Fuel Droplets at High Temperatures

open access: yesEnergies
Examining fuel droplet evaporation is crucial for enhancing fuel engine efficiency, conserving energy, and reducing emissions. This study utilizes experimental methods involving ultrasonic standing wave levitation and high-speed cameras to investigate ...
Bin Pang   +8 more
doaj   +1 more source

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