Results 81 to 90 of about 9,909,879 (292)
Newsletter discussing updates, news, and events for the Model Engine Collectors' Association as well as topics of interest to ...
Model Engine Collectors' Association
core +2 more sources
Introduction. An internal combustion engine is a complex unit, the performance of which is closely related to the functionality of various control systems, in particular electronic ones.
V. D. Gabidulin +2 more
doaj +1 more source
METHOD OF CONVERSION OF HIGH- AND MIDDLE-SPEED DIESEL ENGINES INTO GAS DIESEL ENGINES
The paper aims at the development of fuel supply and electronic control systems for boosted high- and middle-speed transport engines. A detailed analysis of different ways of converting diesel engine to operate on natural gas was carried out.
Mikhail G. Shatrov +4 more
doaj +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Newsletter discussing updates, news, and events for the Model Engine Collectors' Association as well as topics of interest to ...
Model Engine Collectors' Association
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Detection of Diesel Engine Injector Faults Using Acoustic Emissions [PDF]
This study investigated the method of identifying injector faults in a JCB 444T2 diesel engine using acoustic emission (AE) technique. Different kinds of injector faults were seeded in the four-cylinder, four-stroke, and turbo-engine.
Gu, Fengshou +3 more
core +4 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

