Results 41 to 50 of about 82,857 (303)
Potential benefits and risks of clinical xenotransplantation [PDF]
The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
core +2 more sources
Challenges in Cardiac Tissue Engineering [PDF]
Cardiac tissue engineering aims to create functional tissue constructs that can reestablish the structure and function of injured myocardium. Engineered constructs can also serve as high-fidelity models for studies of cardiac development and disease. In a general case, the biological potential of the cell-the actual "tissue engineer"-is mobilized by ...
Gordana, Vunjak-Novakovic +6 more
openaire +2 more sources
The administration of extracellular vesicles (EV) from mesenchymal stromal cells (MSC) is a promising cell-free nanotherapy for tissue repair after myocardial infarction (MI). However, the optimal EV delivery strategy remains undetermined.
Marta Monguió-Tortajada +13 more
doaj +1 more source
In the past two decades, relevant advances have been made in the generation of engineered cardiac constructs to be used as functional in vitro models for cardiac research or drug testing, and with the ultimate but still challenging goal of repairing the ...
Diana Massai +22 more
doaj +1 more source
Towards a Tissue-Engineered Contractile Fontan-Conduit: The Fate of Cardiac Myocytes in the Subpulmonary Circulation. [PDF]
The long-term outcome of patients with single ventricles improved over time, but remains poor compared to other congenital heart lesions with biventricular circulation.
Daniel Biermann +14 more
doaj +1 more source
Electrospun Acellular Heart ECM for Cardiac Tissue Engineering [PDF]
Electrospun nanofiber is one of the promising alternatives for use in tissue engineering and drug delivery due to its controllable characteristics. However, choosing an appropriate biomaterial for a specific tissue regeneration plays a significant role ...
Sh. mashayekhiyan +5 more
doaj +1 more source
An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors. [PDF]
Unlike some organs, the heart is unable to repair itself after injury. Human embryonic stem cells (hESCs) grow and divide indefinitely while maintaining the potential to develop into many tissues of the body.
Bernstein, Harold S +7 more
core +4 more sources
Computational fluid dynamic analysis of bioprinted self-supporting perfused tissue models [PDF]
Natural tissues are incorporated with vasculature, which is further integrated with a cardiovascular system responsible for driving perfusion of nutrient‐rich oxygenated blood through the vasculature to support cell metabolism within most cell‐dense ...
Bonewald, Lynda F. +8 more
core +1 more source
Cardiac Tissue Engineering for the Treatment of Myocardial Infarction
Poor cell engraftment rate is one of the primary factors limiting the effectiveness of cell transfer therapy for cardiac repair. Recent studies have shown that the combination of cell-based therapy and tissue engineering technology can improve stem cell ...
Dongmin Yu, Xiaowei Wang, Lei Ye
doaj +1 more source
Virtual cardiac monolayers for electrical wave propagation [PDF]
The complex structure of cardiac tissue is considered to be one of the main determinants of an arrhythmogenic substrate. This study is aimed at developing the first mathematical model to describe the formation of cardiac tissue, using a joint in silico ...
Agladze, Konstantin +3 more
core +1 more source

