Results 41 to 50 of about 82,857 (303)

Potential benefits and risks of clinical xenotransplantation [PDF]

open access: yes, 2012
The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
core   +2 more sources

Challenges in Cardiac Tissue Engineering [PDF]

open access: yesTissue Engineering Part B: Reviews, 2010
Cardiac tissue engineering aims to create functional tissue constructs that can reestablish the structure and function of injured myocardium. Engineered constructs can also serve as high-fidelity models for studies of cardiac development and disease. In a general case, the biological potential of the cell-the actual "tissue engineer"-is mobilized by ...
Gordana, Vunjak-Novakovic   +6 more
openaire   +2 more sources

Local administration of porcine immunomodulatory, chemotactic and angiogenic extracellular vesicles using engineered cardiac scaffolds for myocardial infarction

open access: yesBioactive Materials, 2021
The administration of extracellular vesicles (EV) from mesenchymal stromal cells (MSC) is a promising cell-free nanotherapy for tissue repair after myocardial infarction (MI). However, the optimal EV delivery strategy remains undetermined.
Marta Monguió-Tortajada   +13 more
doaj   +1 more source

Bioreactor Platform for Biomimetic Culture and in situ Monitoring of the Mechanical Response of in vitro Engineered Models of Cardiac Tissue

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
In the past two decades, relevant advances have been made in the generation of engineered cardiac constructs to be used as functional in vitro models for cardiac research or drug testing, and with the ultimate but still challenging goal of repairing the ...
Diana Massai   +22 more
doaj   +1 more source

Towards a Tissue-Engineered Contractile Fontan-Conduit: The Fate of Cardiac Myocytes in the Subpulmonary Circulation. [PDF]

open access: yesPLoS ONE, 2016
The long-term outcome of patients with single ventricles improved over time, but remains poor compared to other congenital heart lesions with biventricular circulation.
Daniel Biermann   +14 more
doaj   +1 more source

Electrospun Acellular Heart ECM for Cardiac Tissue Engineering [PDF]

open access: yesIranian Journal of Chemical Engineering, 2021
Electrospun nanofiber is one of the promising alternatives for use in tissue engineering and drug delivery due to its controllable characteristics. However, choosing an appropriate biomaterial for a specific tissue regeneration plays a significant role ...
Sh. mashayekhiyan   +5 more
doaj   +1 more source

An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors. [PDF]

open access: yes, 2011
Unlike some organs, the heart is unable to repair itself after injury. Human embryonic stem cells (hESCs) grow and divide indefinitely while maintaining the potential to develop into many tissues of the body.
Bernstein, Harold S   +7 more
core   +4 more sources

Computational fluid dynamic analysis of bioprinted self-supporting perfused tissue models [PDF]

open access: yes, 2020
Natural tissues are incorporated with vasculature, which is further integrated with a cardiovascular system responsible for driving perfusion of nutrient‐rich oxygenated blood through the vasculature to support cell metabolism within most cell‐dense ...
Bonewald, Lynda F.   +8 more
core   +1 more source

Cardiac Tissue Engineering for the Treatment of Myocardial Infarction

open access: yesJournal of Cardiovascular Development and Disease, 2021
Poor cell engraftment rate is one of the primary factors limiting the effectiveness of cell transfer therapy for cardiac repair. Recent studies have shown that the combination of cell-based therapy and tissue engineering technology can improve stem cell ...
Dongmin Yu, Xiaowei Wang, Lei Ye
doaj   +1 more source

Virtual cardiac monolayers for electrical wave propagation [PDF]

open access: yes, 2017
The complex structure of cardiac tissue is considered to be one of the main determinants of an arrhythmogenic substrate. This study is aimed at developing the first mathematical model to describe the formation of cardiac tissue, using a joint in silico ...
Agladze, Konstantin   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy