Results 21 to 30 of about 2,612,478 (275)
Age-dependent functional crosstalk between cardiac fibroblasts and cardiomyocytes in a 3D engineered cardiac tissue. [PDF]
Li Y, Asfour H, Bursac N.
europepmc +2 more sources
Cardiac Tissue Engineering [PDF]
The first 2 reviews in this series have described the defining properties of stem cells, their possible sources, and some initial attempts at their clinical use for tissue regeneration and repair. This third and final article in the series describes bioengineering methods for building physical structures to contain and organize implanted cells.
Matthew W, Curtis, Brenda, Russell
openaire +2 more sources
Summary: Cardiac in vitro models have become increasingly obtainable and affordable with the optimization of human pluripotent stem cell-derived cardiomyocyte (hPSC-CM) differentiation.
Shangli Cheng +10 more
doaj +1 more source
Combining tissue engineering and optical imaging approaches to explore interactions along the neuro-cardiac axis [PDF]
Interactions along the neuro-cardiac axis are being explored with regard to their involvement in cardiac diseases, including catecholaminergic polymorphic ventricular tachycardia, hypertension, atrial fibrillation, long QT syndrome and sudden death in ...
Charalampos Sigalas +7 more
doaj +1 more source
Engineering virtual cardiac tissue [PDF]
The kinetics of proteins involved in ion transfer, sequestration and binding in cardiac cells can be modelled to construct a model of the electrical activity of isolated cardiac cells as a system of ordinary differential equations. These cell models may be incorporated into tissue models, which, when combined with histology and anatomy, form virtual ...
Boyett, M. R., Holden, A. V., Zhang, H.
openaire +4 more sources
Challenges in Cardiac Tissue Engineering [PDF]
Cardiac tissue engineering aims to create functional tissue constructs that can reestablish the structure and function of injured myocardium. Engineered constructs can also serve as high-fidelity models for studies of cardiac development and disease. In a general case, the biological potential of the cell-the actual "tissue engineer"-is mobilized by ...
Gordana, Vunjak-Novakovic +6 more
openaire +2 more sources
Many research groups have developed various types of tissue-engineered cardiac constructs. However, the immunological properties of such artificial tissues are not yet fully understood.
David Sergeevichev +6 more
doaj +1 more source
Functional Cardiac Tissue Engineering [PDF]
Heart attack remains the leading cause of death in both men and women worldwide. Stem cell-based therapies, including the use of engineered cardiac tissues, have the potential to treat the massive cell loss and pathological remodeling resulting from heart attack.
Brian, Liau +2 more
openaire +2 more sources
Recent progress in implantations of differentiated cardiac and non-cardiac cells as well as adult stem cells into the heart suggests that the irreversible loss of viable cardiac myocytes that occurs during myocardial infarction can be at least partly substituted.
Eschenhagen, Thomas +4 more
openaire +5 more sources
Engineered Human Cardiac Tissue [PDF]
The human heart is the first organ to develop during embryogenesis and is arguably the most essential organ for life. However, after birth, the heart has very little capacity to repair malformations such as congenital heart defects or to regenerate after an injury such as myocardial infarction.
Kareen L, Kreutziger, Charles E, Murry
openaire +2 more sources

