Results 81 to 90 of about 819,536 (350)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Profession-oriented textbook of English for engineering students as a tool for developing the axiological component of prospective specialist’s professional culture

Вестник Тамбовского университета. Серия: Гуманитарные науки
Importance. The important issue of developing profession-oriented foreign language textbooks for students of non-linguistic fields of study, in which the acquisition of foreign language communicative skills could be accompanied by the formation of ...
M. G. Evdokimova, E. S. Davidenko
doaj   +1 more source

Employer and student perspectives on skills for engineers in the twenty first century and beyond [PDF]

, 2010
This research focused on skills identified among final year engineering students. It provided evidence of different levels of skills by students and identifies their greatest learning influences in these areas.
Brabazon, Dermot, McMorrow, Denise, Naher, Sumsun   +2 more
core  

Ethical and Social Aspects of Self-Driving Cars

, 2018
As an envisaged future of transportation, self-driving cars are being discussed from various perspectives, including social, economical, engineering, computer science, design, and ethics.
Dodig-Crnkovic, Gordana, Holstein, Tobias, Pelliccione, Patrizio   +2 more
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Soft skills for engineering students and graduates

آموزش مهندسی ایران, 2019
The purpose of this study was to investigate the compliance of electrical engineering ethics codes among students of electrical faculty of Tabriz University and its related factors.
Ali Mohammadzadeh, Rahmat Sotudeh gharebagh   +1 more
doaj   +1 more source

We Could, but Should We? Ethical Considerations for Providing Access to GeoCities and Other Historical Digital Collections [PDF]

, 2020
We live in an era in which the ways that we can make sense of our past are evolving as more artifacts from that past become digital. At the same time, the responsibilities of traditional gatekeepers who have negotiated the ethics of historical data ...
Bastian M., Cohen D., Dent P., Frankel C., Hallinan B., Jenkins H., Klein E., Lin J., McTavish S., Milligan I., Milligan I., Smith M.   +11 more
core   +1 more source

Teaching Engineering Ethics With The Engineering Ethics Challenge Game [PDF]

2005 Annual Conference Proceedings, 2020
Comment: 13 ...
openaire   +2 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source