Results 71 to 80 of about 4,743,133 (351)

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Reuse through rapid development [PDF]

open access: yes, 2007
The general issue of reuse of digital resources, called Learning Objects (LOs), in education is discussed here. Ideas are drawn from software engineering which has long grappled with the reuse problem.
Costello, Eamon
core  

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Ethics – research, engineering, design… they’re all the same aren’t they? [PDF]

open access: yes, 2014
This paper considers how and to what extent product design ethics is understood by professionals in design practice and undergraduate students of product and engineering design and how, if at all, design ethics differ from engineering and/or research ...
Blount, G.   +2 more
core  

An innovative collaborative high-performance platform for simulation [PDF]

open access: yes, 2011
This paper presents an innovative collaborative visualization platform for the simulation-based design applications. Following the scope and the main objectives, the general architecture based on the internet standard technologies is explained.
Alloula, Karim   +4 more
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

A Comparison of Beginning and Advanced Engineering Students’ Description of Information Skills

open access: yesEvidence Based Library and Information Practice, 2015
Objective – The purpose of this research was to examine how beginning and advanced level engineering students report use of information when completing an engineering design process.
Kerrie Anna Douglas   +4 more
doaj   +1 more source

Functional planning and occupational safety of milk production in cold loose housing barns [PDF]

open access: yes, 2004
The study charted the most serious occupational hazards of cold loose housing barns. Furthermore, the study gave a good general picture of cold loose housing barns (CLHB) in dairy production.
Karttunen, Janne
core  

Plasmonic engineering of singlet oxygen generation [PDF]

open access: yesProceedings of the National Academy of Sciences, 2008
In this article, we report metal-enhanced singlet oxygen generation (ME 1 O 2 ). We demonstrate a direct relationship between the singlet oxygen yield of a common photosensitizer (Rose Bengal) and the theoretical electric field enhancement or enhanced absorption of the photosensitizer in ...
Chris D. Geddes   +3 more
openaire   +3 more sources

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Home - About - Disclaimer - Privacy