Results 71 to 80 of about 25,949 (261)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Frontiers in PsychologyEngineering thinking has become a central goal of undergraduate engineering education, yet the psychological pathways through which it emerges in design-oriented course contexts are not well understood. This study examined how self-efficacy is associated
Fang Chen +4 more
doaj +1 more source
Thinking on the Development of Software Engineering Technology [PDF]
Journal of Software, 2005 Summary: The paper gives some thinking according to the following four aspects: 1) from the law of things development, revealing the development history of software engineering technology; 2) from the point of software natural characteristic, analyzing the construction of every abstraction layer of virtual machine; 3) from the point of software ...
openaire +2 more sources
Autonomy for Ships: System Thinking and Engineering
2022 International Conference on Software, Telecommunications and Computer Networks (SoftCOM), 2022 Marine autonomy research has focused on algorithmic and technical developments, targeting autonomous craft in restricted areas where international rules and regulations are not prioritised. This paper addresses the system engineering aspect of a highly complex system in which the seamless, predictable, and secure interoperability of vendorspecific ...
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Asian Journal of Assessment in Teaching and Learning, 2020 This research paper presents the outcome of a research conducted to assess and determine the Validity and Reliability coefficient of Creative Thinking Skills for Conceptual Engineering Design Module administered to engineering undergraduates at a private
Yaw Long Chua +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Systems practice in engineering: reflections on doctoral level systems supervision
, 2011 The Industrial Doctorate Centre (IDC) in Systems, a collaboration between the University of Bristol and the University of Bath, offers an Engineering Doctorate (EngD) in Systems Programme which is aimed at high-calibre engineers from graduate level to ...
Yearworth, M, Yearworth, Mike
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Evidence of Sociotechnical Thinking in Engineering Students
, 2022 The ability to acknowledge and respond to the combination of the social and technical aspects of structures and processes encompassed in engineering design is called Sociotechnical Thinking (STT).
Bezerra Rodrigues, Renato +3 more
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