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Transcriptional control by enhancers and enhancer RNAs [PDF]

open access: yesTranscription, 2019
The regulation of gene expression is a fundamental cellular process and its misregulation is a key component of disease. Enhancers are one of the most salient regulatory elements in the genome and help orchestrate proper spatiotemporal gene expression during development, in homeostasis, and in response to signaling.
Hector L Franco, Michael Lewis
exaly   +3 more sources
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ENHANCING EVOLUTION AND ENHANCING EVOLUTION

Bioethics, 2010
ABSTRACTIt has been claimed in several places that the new genetic technologies allow humanity to achieve in a generation or two what might take natural selection hundreds of millennia in respect of the elimination of certain diseases and an increase in traits such as intelligence.
openaire   +3 more sources

Are “Genetic Enhancements” Really Enhancements?

Cambridge Quarterly of Healthcare Ethics, 2000
The word enhancement is value laden and potentially misleading in the context of genetics. Dictionary definitions of enhance include “increase in value,” “improve,” “appreciate,” and “inflate.” The term genetic enhancement would be better replaced with a more neutral term such as “genetic manipulation” to reflect the fact that the consequences ...
openaire   +2 more sources

Adaptive contrast enhancement and de-enhancement

Pattern Recognition, 1991
Abstract Two different interpolative schemes for adaptive contrast enhancement have been presented for speeding up the contrast enhancement algorithm proposed by Beghdadi and Negrate. To reduce the enhancement of noise in relatively flat regions present in the image, an adaptive power variation technique is used in which the degree of contrast ...
Laxmikant Dash, Biswanath N. Chatterji
openaire   +1 more source

Blackness Enhancement

Perceptual and Motor Skills, 1991
Since apparent brightness increases as an intermittent luminous source decreases from flicker fusion to approximately 10 cps, the phenomenal blackness induced by an intermittent annulus should also increase as a result of brightness contrast. However, data from 5 observers showed the phenomenal blackness occurring with a 10-cps inducer was greater than
W L, Brigner, J R, Deni
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Enhanced hypercubes

IEEE Transactions on Computers, 1991
A hypercube with extra connections added between pairs of nodes through otherwise unused links is investigated. The extra connections are made in a way that maximizes the improvement of the performance measure of interest under various traffic distributions. The resulting hypercube, called the enhanced hypercube, requires a simple routing algorithm and
Nian-Feng Tzeng, Sizheng Wei
openaire   +1 more source

LASIK Enhancements

International Ophthalmology Clinics, 2000
As the field of refractive surgery continues to evolve, an increasing number of surgical options are available for LASIK enhancements. Nonetheless, older methods such as AK continue to play an important role in enhancement procedures. Improvements in instruments and techniques allow for previously made LASIK flaps to be safely lifted for additional ...
D S, Durrie, T L, Vande Garde
openaire   +2 more sources

The enhanced warfighter

Bulletin of the Atomic Scientists, 2014
Modern technological warfare requires a level of cognitive ability and discipline unique in the history of armed conflict. Recent advances in physiology, nutrition, neuroscience, and engineering offer a significant potential to prevent or reduce the degradation of a warfighter’s mental or physical capabilities in this demanding environment. The authors
Kenneth Ford, Clark Glymour
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Enhancer Transcription And Enhancer Function

The FASEB Journal, 2016
We utilize a combination of genome‐wide and genetic approaches to investigate molecular mechanisms that underlie the development and function of macrophages. Our studies suggest a relatively simple model of hierarchical interactions between lineage‐determining and signal‐dependent transcription factors that are required to select functional cis‐active ...
Christopher Glass   +6 more
openaire   +1 more source

Enhancing Learning by Enhancing Teaching

2015
This chapter provides an overview of the enhancement of teaching and learning in a higher education setting, facilitated by two enhancement initiatives. The PRO-Teaching project and the PACES are complementary cross-disciplinary teamimplemented initiatives aimed at enhancing the quality of teaching and curriculum design.
Klopper, Christopher   +2 more
openaire   +1 more source

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