Results 241 to 250 of about 2,230,930 (359)

Cohesin forms fountains at active enhancers in C. elegans. [PDF]

Nat Commun
Lüthi BN, Semple JI, Haemmerli A, Thapliyal S, Ghadage K, Stojanovski K, D'Asaro D, Das M, Gilbert N, Glauser DA, Towbin B, Jost D, Meister P.   +12 more
europepmc   +1 more source

Push by a net, pull by a cow: can zooprophylaxis enhance the impact of insecticide treated bed nets on malaria control? [PDF]

, 2014
Hanako Iwashita, Gabriel O. Dida, George Sonye, Toshihiko Sunahara, Kyoko Futami, Sammy M. Njenga, Luis Fernando Chaves, Noboru Minakawa   +7 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Comprehensive evaluation of diverse massively parallel reporter assays to functionally characterize human enhancers genome-wide. [PDF]

Genome Biol
Zhang J, Leung AK, Zhu Y, Yao L, Willis A, Pan X, Ozer A, Zhou Z, Siklenka K, Barrera A, Liang J, Tippens ND, Reddy TE, Lis JT, Yu H.   +14 more
europepmc   +1 more source

Highlighting enhancers [PDF]

Nature Methods, 2011
openaire   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Interaction Between Enhancers and Promoters in Chicken Genome. [PDF]

Int J Mol Sci
Grushina VA, Filatova AP, Gagarina VS, Prasolov DE, Kolpakov FA, Gusev OA, Pintus SS.   +6 more
europepmc   +1 more source

Transcriptional regulation of the tyrosine aminotransferase gene [PDF]

, 1989
Boshart, Michael, Dumont, J. E., Nitsch, Doris, Nunez, J., Schmidt, Andrea, Schütz, Günther, Weih, Falk   +6 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Temporal constraints on enhancer usage shape the regulation of limb gene transcription. [PDF]

Nat Commun
Rouco R, Rauseo A, Darbellay F, Sapin G, Bompadre O, Lopez-Delisle L, Andrey G.   +6 more
europepmc   +1 more source