Results 311 to 320 of about 8,934,200 (403)

Non-penetrant Xq26.3 duplication involving the invariant TAD border: clinical evidence for the VGLL1 region as the GPR101 pituitary enhancer of X-linked acrogigantism. [PDF]

Pituitary
Hilditch C, Curtis S, Cotton S, LeBlanc S, De Sousa S.   +4 more
europepmc   +1 more source

Transcriptional regulation of the tyrosine aminotransferase gene [PDF]

, 1989
Boshart, Michael, Dumont, J. E., Nitsch, Doris, Nunez, J., Schmidt, Andrea, Schütz, Günther, Weih, Falk   +6 more
core  

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Analysis of biased allelic enhancer activity of schizophrenia-linked common variants. [PDF]

Commun Biol
Gao C, Zhang Q, Wu C, Peng L, Wu M, Wang B, Xue B, Niu M, Jiang Y, Yuan W, Song H, Li X, Zhao X, Niu Y, Sun Y, Ding Y, Li Z.   +16 more
europepmc   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Cell type differences in human cytomegalovirus transcription and epigenetic regulation with insights into major immediate-early enhancer-promoter control. [PDF]

PLoS Pathog
Hu Q, Li M, Parida M, Spector BM, Santana JF, Zandvakili A, Price DH, Meier JL.   +7 more
europepmc   +1 more source

Depressors of Interferon Synthesis: Further Studies on the Production, Action and Properties of the So-called Enhancer

, 1969
N. Kato, Hans J. Eggers, Fujito Ohta, Takeshi Kobayashi   +3 more
openalex   +1 more source

Enhancing Me, Enhancing You: Academic Enhancement as a Moral Duty

Expositions, 2009
openaire   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Discovery of NANOG enhancers and their essential roles in self-renewal and differentiation in human embryonic stem cells. [PDF]

Stem Cell Reports
Yan J, Luo R, Rosen BP, Liu D, Wong W, Leslie CS, Huangfu D.   +6 more
europepmc   +1 more source