Results 81 to 90 of about 8,887,574 (403)
Enhancing Moral Conformity and Enhancing Moral Worth [PDF]
Neuroethics, 2013 It is plausible that we have moral reasons to become better at conforming to our moral reasons. However, it is not always clear what means to greater moral conformity we should adopt. John Harris has recently argued that we have reason to adopt traditional, deliberative means in preference to means that alter our affective or conative states directly ...
Thomas Douglas, Thomas Douglas
openaire +4 more sources
BioEssays, 2023 AbstractTight control of the transcription process is essential for the correct spatial and temporal gene expression pattern during development and in homeostasis. Enhancers are at the core of correct transcriptional activation. The original definition of an enhancer is straightforward: a DNA sequence that activates transcription independent of ...
Henry Fabian Thomas, Christa Buecker
openaire +3 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Targeted screening of genetic associations with COVID-19 susceptibility and severity
Frontiers in Genetics, 2022 The COVID-19 pandemic has resulted in great morbidity and mortality worldwide and human genetic factors have been implicated in the susceptibility and severity of COVID-19.
Ping Li +9 more
doaj +1 more source
eLife, 2017 Laboratory mice with over half a megabase of DNA upstream of their Myc gene removed still thrive in the absence of stress.
Ying Zheng, David Levens
openaire +4 more sources
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
DIMETILSULFOKSID SEBAGAI ENHANCER TRANSPOR TRANSDERMAL TEOFILIN SEDIAAN GEL
Pharmaciana, 2013 Dimethylsulfoxide (DMSO) has been intensively studied the 19th century. This substance is used as a medicine and solve. It can also be used as an absorption enhancer of various drugs, either synthetical or herbal medicines.
Resty Annisa Damayanti, Tedjo Yuwono
doaj +1 more source
eLife, 2023 Cancer is driven by both genetic and epigenetic changes that impact on gene expression profiles and the resulting tumourigenic phenotype. Enhancers are transcriptional regulatory elements that are key to our understanding of how this rewiring of gene ...
Ibrahim Ahmed +6 more
doaj +1 more source
Lithium from mood stabilizer to putative cognitive enhancer [PDF]
, 2016 This study is the first to have demonstrated, by means of a highly sensitive test of visual memory, a potential hippocampus neuroprotective effect of lithium in patients with BD. Undoubtedly, other studies are needed to finally recognize lithium as a
Bersani, Giuseppe +2 more
core +2 more sources
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source