Results 101 to 110 of about 9,293,313 (313)
Five novel cis-regulatory deletions of SOX10 cause Waardenburg syndrome type II
Frontiers in Audiology and OtologyIntroductionWaardenburg syndrome (WS) is a genetic disorder characterized by hearing loss, hypopigmentation, and distinct facial features. Despite > 60% molecular diagnosis rate for WS patients, pathogenic variants within coding regions are ...
Yu Huang +22 more
doaj +1 more source
Epigenetics, 2018 Recent studies have revealed an unexpected role of DNA methylation at promoter regions in transcription activation. However, whether DNA methylation at enhancer regions activates gene expression and influences cellular functions remains to be determined.
Olutobi Oyinlade +10 more
doaj +1 more source
Proceedings of the AAAI Conference on Artificial Intelligence and Interactive Digital Entertainment, 2007 In video games, pathfinding must be done quickly and accurately. Not much computational time is allowed for pathfinding, but realistic looking paths are required. One approach to pathfinding which attempts to satisfy both of these constraints is to perform pathfinding on abstractions of the map.
M. Renee Jansen, Michael Buro
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT The International Paediatric Oncology Society Global Mapping Programme aims to collect data on global paediatric oncology services by continent, with Africa and Latin America completed. This study reports on the methodology and lessons learned for Oceania, a unique continent with resource disparity across countries, multiple small island ...
Trisha Soosay Raj +16 more
wiley +1 more source
Frontiers in GeneticsIntroduction: Transcriptional regulation is an important process wherein non-protein coding enhancer sequences play a key role in determining cell type identity and phenotypic diversity.
Ashley R. Brown +27 more
doaj +1 more source
Enhancer features that drive formation of transcriptional condensates
bioRxiv, 2018 Enhancers, DNA elements that regulate gene expression, contain transcription factor (TF) binding sites. TFs bind short sequence motifs that are present throughout the genome at much higher frequency than active enhancers, and so the features that define ...
K. Shrinivas +10 more
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin +6 more
wiley +1 more source
Streamlined scanning for enhancer elements in Drosophila melanogaster
BioTechniques, 2016 Enhancer elements in most eukaryotic organisms are often positioned at a great distance away from the transcription start site of the gene they regulate. Complex three-dimensional chromatin organization and insulators usually guide and limit the range of
Roumen Voutev, Richard S. Mann
doaj +1 more source
Modification of enhancer chromatin: what, how and why?
Molecules and Cells, 2013 Emergence of form and function during embryogenesis arises in large part through cell type- and cell state- specific variation in gene expression patterns, mediated by specialized cis-regulatory elements called enhancers.
Eliezer Calo, J. Wysocka
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Animal‐assisted activities (AAAs) with therapy dogs have shown positive effects on patient well‐being and quality of life in various areas of medicine, including pediatric oncology. However, research on this topic is limited. The aim of this study is to present the current status of AAA in pediatric oncology in Germany, Austria, and
Jan‐Marius Wedig +7 more
wiley +1 more source