Results 261 to 270 of about 4,995,766 (296)
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Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9

Nature Biotechnology, 2016
Systematic identification of noncoding regulatory elements has, to date, mainly relied on large-scale reporter assays that do not reproduce endogenous conditions. We present two distinct CRISPR-Cas9 genetic screens to identify and characterize functional enhancers in their native context.
Reuven Agami   +2 more
exaly   +3 more sources

Enhanced removal of antibiotic resistance genes and mobile genetic elements during swine manure composting inoculated with mature compost

Journal of Hazardous Materials, 2021
Livestock manure is a major source of antibiotic resistance genes (ARGs) that enter the environment. This study assessed the effects of inoculation with mature compost (MC) on the fates of ARGs and the bacterial community during swine manure composting.
Jia, Wang   +8 more
openaire   +2 more sources

Linezolid resistance genes and genetic elements enhancing their dissemination in enterococci and streptococci

Plasmid, 2018
Linezolid is considered a last resort drug in treatment of severe infections caused by Gram-positive pathogens, resistant to other antibiotics, such as vancomycin-resistant enterococci (VRE), methicillin-resistant staphylococci and multidrug resistant pneumococci.
openaire   +2 more sources

Enhanced removal of antibiotic resistance genes and mobile genetic elements during sewage sludge composting covered with a semi-permeable membrane

Journal of Hazardous Materials, 2020
Transmission of antibiotic resistance genes (ARGs) via air media, such as particulate matter, has been intensively investigated due to human exposure through inhalation. However, whether particulate matter originating from the atmospheric environment of composting plants can impact ARG abundance during composting is unknown.
Peng Cui   +11 more
openaire   +2 more sources

Agents that enhance or reduce movement of mobile genetic elements: Detection in microbial assays and implications for toxicological assessment

Environmental Toxicology and Water Quality, 1993
AbstractA comprehensive assessment of the potential toxicological effects of an environmental chemical or mixture of chemicals must take into account the possibility of genetic damage to cellular organisms. In conventional assays (e.g., the Ames test), point mutations (both base‐pair substitutions and frameshifts) have come into widespread use as ...
openaire   +1 more source

An Innovative Genetic-Algorithm-Based Method for Designing a Compact Wideband Four-Element MIMO Antenna with Enhanced Isolation

The following paper discusses a compact and broadband four element MIMO antenna for the 5G NR n79 band application. The design was optimized by considering the radiating patches along with the metamaterial decoupling structure through the binary genetic algorithm (GA) to ensure that the desired impedance bandwidth and high isolation between elements ...
OMAR OURAHOU   +4 more
openaire   +1 more source

Identification of Novel Germplasm and Genetic Loci for Enhancing Mineral Element Uptake in Soybean

2023
Suhas Shinde   +11 more
openaire   +1 more source

Optimizing powder compaction for enhanced relative density: Insights from multi-particle finite element simulations and genetic algorithm

Materials Research Proceedings
Abstract. In this study, multi-particle finite element simulations in powder compaction were performed to analyze the effects of the size of the representative volume element (RVE), the number of elements per particle, and particle size distribution. Simulation parameters were calibrated to accurately predict the relative density of compacts derived ...
openaire   +1 more source

Genetic testing in prostate cancer management: Considerations informing primary care

Ca-A Cancer Journal for Clinicians, 2022
Todd M Morgan   +2 more
exaly  

Genetic Variation in Enhancers Modifies Cardiomyopathy Gene Expression and Progression

Circulation, 2021
Dominic E Fullenkamp   +2 more
exaly  

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