Results 131 to 140 of about 79,525 (194)

The Leucine-mTOR-Autophagy Axis in Granulosa Cells Mediates Circadian Disruption-Induced Anovulation. [PDF]

Int J Biol Sci
He R, Mo J, Lin Z, Zhu K, Wang Y, Yu J, Wu H, Jiang Z, Luo Q, Liu X, Yin L, Yu C, Sheng J, Ding G, Huang H.   +14 more
europepmc   +1 more source

Untargeted Sweat Metabolomics and Targeted Plasma Amino Acid Profiling Reveal Dynamic Metabolic Remodeling During Conditioning in <i>Yili</i> Horses. [PDF]

Biology (Basel)
Xue Y, Luo P, Shen Z, Meng C, Yao X, Meng J, Ren W, Wang T, Zeng Y.   +8 more
europepmc   +1 more source

Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study. [PDF]

Exp Ther Med
Yao JY, Tzeng DT, Feng CH, Xiao GM, You TN, Zheng RY.   +5 more
europepmc   +1 more source

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RAPID LEUCINE‐ENKEPHALIN SYNTHESIS

International Journal of Peptide and Protein Research, 1980
Leucine‐enkephalin, a naturally occurring pentapeptide with morphine‐like activity, has been synthesized by a fragment condensation liquid phase method using 3,3,4‐trimethyl‐Δ3‐phospholene‐1,1‐dichloride as a coupling agent. The advantages of this method are discussed.
E, Vilkas, M, Vilkas, J, Sainton
openaire   +2 more sources

Crystal structure of leucine-enkephalin

Nature, 1983
The crystal structure of leucine-enkephalin has been determined in a crystal form that has four independent enkephalin molecules and much water and dimethylformamide solvent in the asymmetric unit. All four enkephalins have extended peptide backbones with the Tyr, Phe and Leu side chains above and below the plane of the backbone. There is evidence that
A, Camerman, D, Mastropaolo, I, Karle, J, Karle, N, Camerman   +4 more
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Monoclonal antibodies to leucine enkephalin

Biochemical and Biophysical Research Communications, 1983
Monoclonal antibodies to leucine enkephalin have been produced after fusion of mouse myeloma cells with spleen cells from hyper-immune mice. Hybrid clones 2D1 and SL1 were characterised using radioimmunoassay and an enzyme-linked immunosorbent assay. The antibody 2D1 was of low affinity and showed a maximum sensitivity of 0.1ng.
C A, Jones, D P, Lane, J, Hughes
openaire   +2 more sources

The potentiation of spinal analgesia by leucine enkephalin

European Journal of Pharmacology, 1980
In two strains of rats, intrathecal administration of morphine and met-enkephalin was found to produce a dose-dependent analgesic effect as measured by the tail-flick assay. Prior administration of leu-enkelphalin at a dose which had no analgesic effect was found to reduce significantly the analgesic ED50 of both morphine and met-enkephalin.
A A, Larson, J L, Vaught, A E, Takemori
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A heterocyclic analog of leucine‐enkephalin

Journal of Heterocyclic Chemistry, 1987
AbstractA series of di‐, tri‐, tetra‐ and pentapeptide analogs of leucine‐enkephalin have been prepared in which the initial tyrosinylglycine fragment has been replaced by the 5,6‐dihydro‐5,5‐dimethyl‐2‐oxo‐3‐phenyl‐1(2H)‐pyrazineacetic acid moiety.
Albert A. Carr, Mark W. Dudley, Edward W. Huber, John M. Kane, Francis P. Miller   +4 more
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Plasma Methionine-Enkephalin and Leucine-Enkephalin in Normal Subjects and Patients with Pheochromocytoma*

The Journal of Clinical Endocrinology & Metabolism, 1983
Plasma methionine-enkephalin-like and leucine-enkephalin-like immunoreactivity (met-enkephalin-LI and leu-enkephalin-LI, respectively) in six normal subjects and six patients with pheochromocytoma were determined. The contents of met-enkephalin-LI and leu-enkephalin-LI in two of six pheochromocytomas were 40- to 50-fold higher and those in the other ...
T, Yoshimasa, K, Nakao, S, Li, Y, Ikeda, M, Suda, M, Sakamoto, H, Imura   +6 more
openaire   +2 more sources