Results 141 to 150 of about 79,525 (194)
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Clinical and Experimental Pharmacology and Physiology, 1989
SUMMARY1. A radio‐immunoassay (RIA) for methionine‐enkephalin sulfoxide was developed and was used to measure methionine‐enkephalin, after oxidation, in the rat brain.2. The RIA was performed together with assays that use commercially available met‐and leu‐enkephalin antisera.3.
G K, Tiong, J E, Olley
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SUMMARY1. A radio‐immunoassay (RIA) for methionine‐enkephalin sulfoxide was developed and was used to measure methionine‐enkephalin, after oxidation, in the rat brain.2. The RIA was performed together with assays that use commercially available met‐and leu‐enkephalin antisera.3.
G K, Tiong, J E, Olley
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Hydrolysis of Peripheral Leucine Enkephalin in Allergic Asthma
Clinical Immunology, 1999Plasma hydrolysis of leucine enkephalin was studied in a group of patients affected by seasonal allergic asthma in acute and quiescent stage; data were compared with those obtained from a control group of healthy volunteers. Results obtained indicate a statistically significant reduction of leu-enkephalin hydrolysis in allergic subjects.
L, Fuso +6 more
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A conformational analysis of leucine enkephalin as a function of pH
Biopolymers, 2002AbstractThe conformations of Leu enkephalin in aqueous solution have been investigated as a function of pH using molecular dynamics simulations. The simulations suggest the peptide backbone exists as a mixture of folded and unfolded forms (approximately 50% each) at neutral pH, but is always unfolded at low or high pH.
Mahalaxmi, Aburi, Paul E, Smith
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SYNTHESIS OF CHROMOPHORIC DEHYDRO ANALOG OF LEUCINE ENKEPHALIN
International Journal of Peptide and Protein Research, 1981Dehydropeptides incorporating a highly colored group have been prepared by reacting peptide esters with 4‐(4′‐dimethyl‐amino‐3′‐nitro) benzylidene‐2‐phenyloxazolin‐5‐one. This method allows a rapid synthesis of colored analogs of physiologically important peptides, in this case, leucine enkephalin.
D J, Phelps, J R, Godin
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Distribution of leucine-enkephalin in bone and joint tissues
Neuropeptides, 2002The distribution and concentration of leu-enkephalin in periosteum, cortical bone, bone marrow and synovial membrane of normal rats were analysed. Periosteum, cortical bone and bone marrow of the rat femurs were collected as well as the ankles. The distribution of leu-enkephalin was analysed by immunoelectron microscopy and the concentration of leu ...
Wu, Qinyang +3 more
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Glycation of Leucine-Enkephalin: Imidazolidinones and Amadori Compounds
2001In an effort to elucidate the properties and reactivity of the parent free sugars, herein we present the formation of leucine-enkephalin related imidazolidinones, as well as Amadori compounds from glucose, mannose or galactose and leucine-enkephalin. We will present the influence of solvent , temperature and added base on the rate of formation of these
Horvat, Štefica, Roščić, Maja
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Life Sciences, 1983
Methionine-enkephalin(met-enkephalin)-, leucine-enkephalin(leu-enkephalin)-, methionine-enkephalin-Arg6-Phe7(met-enkephalin-Arg-Phe)- and methionine-enkephalin-Arg6-Gly7-Leu8(met-enkephalin-Arg-Gly-Leu)-like immunoreactivities(-LI) were studied in 16 pheochromocytomas by radioimmunoassays (RIAs) for these four opioid peptides. Met-enkephalin-Arg-Phe-LI
T, Yoshimasa +5 more
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Methionine-enkephalin(met-enkephalin)-, leucine-enkephalin(leu-enkephalin)-, methionine-enkephalin-Arg6-Phe7(met-enkephalin-Arg-Phe)- and methionine-enkephalin-Arg6-Gly7-Leu8(met-enkephalin-Arg-Gly-Leu)-like immunoreactivities(-LI) were studied in 16 pheochromocytomas by radioimmunoassays (RIAs) for these four opioid peptides. Met-enkephalin-Arg-Phe-LI
T, Yoshimasa +5 more
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Secondary ion mass spectra of the neuropeptides leucine-enkephalin and methionine-enkephalin
Biological Mass Spectrometry, 1982Positive and negative secondary ion mass spectra obtained by bombardment of thin films of leucine-enkephalin and methionine-enkephalin with a pulsed beam of Cs+ ions of energy 5–15 keV were recorded using a time-of-flight mass spectrometer. Many of the secondary ions are metastable.
J. B. Westmore, W. Ens, K. G. Standing
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Synthesis of leucine enkephalin derivatives: Structure-function studies
Biochemical and Biophysical Research Communications, 1977Abstract The solid phase synthesis of highly purified [Leu 5 ] enkephalin and of seven derivatives including [Ala 2 ,Leu 5 ]-, [Ser 2 ,Leu 5 ]-, [Ser 3 ,Leu 5 ]-, [Aba 2 ,Leu 5 ]-, and [des-Gly 2(3) ,Leu 5 ]enkephalins are reported, and their morphine-like activities in neuroblastoma x glioma cell homogenates were measured. Changes at the 2, 3, and 5
N S, Agarwal +4 more
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The effects of methionine- and leucine-enkephalin on spinal neurones of the cat
Brain Research, 1979Extra- and intracellular recordings were obtained from physiologically identified, spinal neurones in the 6th and 7th lumbar segments of the pentobarbitone-anaesthetized cat. Microiontophoretically applied methionine- and leucine-enkephalin reversibly inhibited the spontaneous, synaptically induced, and L-glutamate-induced activity in the majority of ...
W, Zieglgänsberger, I F, Tulloch
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