Results 161 to 170 of about 79,525 (194)
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Inhibitory action of iontophoretically applied methionine-enkephalin and leucine-enkephalin on tuberal hypothalamic neurons

Neuroscience Letters, 1978
Abstract The responses of neurons to iontophoretic application of methionine-enkephalin and leucine-enkephalin were tested in the tuberal hypothalamus of the guinea-pig. Both spontaneously active and ‘silent’ units activated by glutamate were investigated. Thirty-six percent of the total population of neurons tested were inhibited by these compounds.
B, Carette, P, Poulain
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Synthesis and biological activity of monothionated analogs of leucine‐enkephalin

International Journal of Peptide and Protein Research, 1984
The synthesis of the four regioisomers of monothionated Leu‐enkephalins (Leu‐Enk) from previously reported protected precursors is described. The Tyr1‐thio analog was obtained as a 1:1 mixture of the L‐ and D‐Tyr diastereomers. The pure compounds were tested for opiate‐like activity by using the guinea‐pig ileum (GPI) and mouse vas deferens (MVD ...
G, Lajoie   +6 more
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Endogenous Signaling Complexity in Neuropeptides- Leucine- and Methionine-Enkephalin

Cellular and Molecular Neurobiology, 2006
1. In addition to his many fine contributions in furthering our understanding of the neurochemical action of ecosanoids, catchelomines, steroids, anandamines, cannabinoids, endorphins, and the many modifications made to these neural factors, twenty years ago Julius Axelrod published a noteworthy paper concerning the nature of neuropeptides and their ...
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Seizures induced by carbachol, morphine, and leucine‐enkephalin: A comparison

Annals of Neurology, 1983
AbstractThe electrical, behavioral, and pharmacological properties of seizures induced by morphine, leucine‐enkephalin, and the muscarinic cholinergic agonist carbachol were examined and compared. Low‐dose carbachol given intracerebroventricularly (ICV) produced seizures similar electrically to those produced by ICV morphine and leucineenkephalin ...
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Leucine as an excipient in spray dried powder for inhalation

Drug Discovery Today, 2021
Nasser Alhajj   +2 more
exaly  

Totalsynthese von Leucin-Enkephalin

Tetrahedron Letters, 1976
Wolfgang Voelter   +2 more
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Acetyl-leucine slows disease progression in lysosomal storage disorders

Brain Communications, 2021
John Spencer   +2 more
exaly  

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