Results 171 to 180 of about 20,144 (188)
Some of the next articles are maybe not open access.
Trauma Decreases Leucine Enkephalin Hydrolysis in Human Plasma
The Journal of Pharmacology and Experimental Therapeutics, 1999Plasma hydrolysis of leucine enkephalin was evaluated, together with several cellular immune parameters, in a homogeneous group of human subjects who had undergone severe trauma (proximal femur fracture); data obtained were compared with those obtained in an age-matched control group.
R, Babst +5 more
openaire +2 more sources
Synthesis of leucine enkephalin derivatives: Structure-function studies
Biochemical and Biophysical Research Communications, 1977Abstract The solid phase synthesis of highly purified [Leu 5 ] enkephalin and of seven derivatives including [Ala 2 ,Leu 5 ]-, [Ser 2 ,Leu 5 ]-, [Ser 3 ,Leu 5 ]-, [Aba 2 ,Leu 5 ]-, and [des-Gly 2(3) ,Leu 5 ]enkephalins are reported, and their morphine-like activities in neuroblastoma x glioma cell homogenates were measured. Changes at the 2, 3, and 5
N S, Agarwal +4 more
openaire +2 more sources
Synthesis and biological evaluation of leucine enkephalin turn mimetics
Organic & Biomolecular Chemistry, 2006A cyclic Leu-enkephalin mimetic containing a 7-membered ring, and two linear analogues, has been prepared on solid phase. In the cyclic mimetic the intramolecular (1-4) hydrogen bond found in crystalline Leu-enkephalin has been replaced by an ethylene bridge.
David, Blomberg +4 more
openaire +2 more sources
Interactions of Leucine-enkephalin with α-Adrenoceptors in the Conscious Dog
Chest, 1983Leucine-enkephalin (Leu-ENK) administered systemically to the conscious dog increases heart rate and blood pressure, a response prevented by naloxone and hence mediated by opiate receptors. Clonidine attenuates the heart rate increase without affecting the pressor response.
T D, Giles, G E, Sander
openaire +2 more sources
Enzyme-linked immunosorbent assay for leucine and methionine enkephalins
Analytical Biochemistry, 1983An enzyme-linked immunosorbent assay for enkephalins was developed by coupling the peptides to a carrier molecule (bovine serum albumin) in order to allow the antibody-antigen reaction to take place in the solid phase. The assay was shown to be highly reproducible.
G, Zamboni, C A, Jones, J, Hughes
openaire +2 more sources
Endogenous Signaling Complexity in Neuropeptides- Leucine- and Methionine-Enkephalin
Cellular and Molecular Neurobiology, 20061. In addition to his many fine contributions in furthering our understanding of the neurochemical action of ecosanoids, catchelomines, steroids, anandamines, cannabinoids, endorphins, and the many modifications made to these neural factors, twenty years ago Julius Axelrod published a noteworthy paper concerning the nature of neuropeptides and their ...
openaire +2 more sources
Seizures induced by carbachol, morphine, and leucine‐enkephalin: A comparison
Annals of Neurology, 1983AbstractThe electrical, behavioral, and pharmacological properties of seizures induced by morphine, leucine‐enkephalin, and the muscarinic cholinergic agonist carbachol were examined and compared. Low‐dose carbachol given intracerebroventricularly (ICV) produced seizures similar electrically to those produced by ICV morphine and leucineenkephalin ...
openaire +2 more sources
Methionine Enkephalin, But not Leucine Enkephalin, is Excreted in Bile
Clinical Science, 1988J.R. Thornton, M.S. Losowsky
openaire +1 more source
Totalsynthese von Leucin-Enkephalin
Tetrahedron Letters, 1976Wolfgang Voelter +2 more
openaire +1 more source
Interactions of Leucine Enkephalin and Narcotics with Opioid Receptors
Molecular Pharmacology, 1981J L, Vaught, T, Kitano, A E, Takemori
openaire +2 more sources