Role of enkephalin derivative in promoting wound healing and scar remodeling via increased epidermal growth factor in a mouse model [PDF]
Background Enkephalin, an endogenous neuropeptide, binds to the delta (δ) opioid receptor and exerts an antinociceptive effect. Recent studies have suggested that neuropeptides might effectuate cutaneous wound healing.
Sun Eung Kim +2 more
doaj +1 more source
Exposure to exogenous enkephalins disrupts reproductive development in the Eastern lubber grasshopper, Romalea microptera (Insecta: Orthoptera). [PDF]
Enkephalins play a major role in reproductive physiology in crustaceans; however their role in reproductive development in insects is largely unknown. We investigated the effect of exposure to exogenous leucine-enkephalin (Leu-Enk), methionine-enkephalin
Sandeep Kumar +4 more
doaj +1 more source
Active site mutations change the cleavage specificity of neprilysin. [PDF]
Neprilysin (NEP), a member of the M13 subgroup of the zinc-dependent endopeptidase family is a membrane bound peptidase capable of cleaving a variety of physiological peptides.
Travis Sexton +4 more
doaj +1 more source
A small number of researches were done in the design and synthesis of enkephalin analogues that are able to resist degradation effect of proteolytic enzymes with good bioavailability and half-lives.Through studying structure activity relationships we ...
Muthanna S. Al-Ttaee +2 more
doaj +3 more sources
Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS). [PDF]
Azithromycin is recommended for the treatment of uncomplicated urogenital chlamydia infection although the standard 1gram dose sometimes fails to eradicate the infection (treatment failure).
Lenka A Vodstrcil +12 more
doaj +1 more source
Tyrosine-arginine (kyotorphin), an opioid analgesic dipeptide, was discovered more than 40 years ago in 1979. The evidence accumulated during this period has established the physiological significance of kyotorphin as a neuromodulating peptide, and ...
Hiroshi Ueda, Hiroshi Ueda, Hiroshi Ueda
doaj +1 more source
Mass Spectrometry Imaging Combined With Single-Cell Transcriptional Profiling Reveals the Multidimensional Spatial Distributions and Biosynthetic Pathways of Medicinal Components in Andrographis paniculata. [PDF]
ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
Zeng H +14 more
europepmc +2 more sources
Enkephalin Leucine Microspheres Suspension as a Sustained Antiplaque Antimicrobial Delivery System
The purpose of this study is to prepare a formulation containing enkephalin leucine as an antiplaque/antibacterial agent. Enkephalin leucine microspheres were prepared using a poly(D-L-lactide-co-glycolide) (PLGA) as a delivery system.
Laith H. Samein
doaj +1 more source
The current study focused on the effect of administration of the neurotransmitter leucine enkephalin on ovarian maturation in the freshwater crab Travancoriana schirnerae.
Navya Gopal, Arath Raghavan Sudha Devi
doaj +1 more source
Porous silica particles were prepared by sol–gel method with some modification to get wide-pore particles. These particles were derivatized with N-phenylmaleimide-methylvinylisocyanate (PMI) and styrene by reversible addition fragmentation chain transfer
Sarah Alharthi +6 more
doaj +1 more source

