Results 41 to 50 of about 20,669 (211)
Excessive exercise induces exercise‐induced fatigue through multiple interconnected mechanisms, including energy shortage and metabolite accumulation, oxidative stress and inflammation, mitochondrial dysfunction, and neuroendocrine strain. Integrative management strategies include nutrition‐based approaches and acupuncture‐based interventions ...
Yaqin Yang +5 more
wiley +1 more source
Clinical trial of electroacupuncture at Neimadian-point for cancer pain
Objective To observe the clinical efficacy and safety of electroacupuncture(EA) at Neimadian-point for cancer pain. Methods A total of 140 cancer patients with pain were randomly divided into EA and control groups, with 70 cases in each group.
HAN Xue-chang +6 more
doaj
Background. This study aimed to investigate the use of human bone marrow mesenchymal stem cells (hBMSCs) genetically engineered with the human proenkephalin (hPPE) gene to treat bone cancer pain (BCP) in a rat model. Methods. Primary cultured hBMSCs were
Yi Sun +4 more
doaj +1 more source
Opioid precursor protein isoform is targeted to the cell nuclei in the human brain [PDF]
Background: Neuropeptide precursors are traditionally viewed as proteins giving rise to small neuropeptide molecules. Prodynorphin (PDYN) is the precursor protein to dynorphins, endogenous ligands for the kappa-opioid receptor.
Alkass, Kanar +15 more
core +2 more sources
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source
A Stepwise Approach to 1,4,10,13‐Tetraaza‐18‐Crown‐6 Ether
A two‐step synthetic strategy to tetraaza‐18‐crown‐6 was developed to overcome the low yield of the conventional one‐step method. Optimized conditions significantly suppressed formation of the undesired nine‐membered ring. A three‐fold increase in yield of the macrocyclization step was obtained, or two‐fold when column chromatography was avoided. A two‐
Pieter Troosters +3 more
wiley +1 more source
Background Mesenchymal stem cell (MSC) has been one of the potential tools in neuropathic pain therapy; however, the augmented efficacy may be expected when they are modified with human proenkephalin ( hPPE ) gene.
Yi Sun +4 more
doaj +1 more source
Oral naltrexone treatment for cholestatic pruritus: A double-blind, placebo-controlled study [PDF]
Background and Aims: The efficacy of currently available therapeutic agents for cholestatic pruritus is often disappointing. The aim of this study was to assess the antipruritic effect of naltrexone, an oral opiate receptor antagonist.
Bertolotti, M. (M.) +5 more
core +4 more sources
Catalytic Autoxidation for Depolymerization of Multilayer Plastic Films
Catalytic autoxidation using a Co/Mn/Br catalyst system depolymerizes diverse polymers in multilayer plastic films, generating oxygenated small molecules such as dicarboxylic acids. The method tolerates additives and disrupters and converts up to 48 mol% polymer carbon into soluble products, enabling chemical recycling of complex plastic waste ...
Ciaran W. Lahive +16 more
wiley +1 more source
Photodissociation of protonated Leucine-Enkephalin peptide in the VUV range
We present results of VUV action spectroscopy of gas-phase protonated Leucin-Enkephalin peptide. The experiment has been performed by coupling a linear quadrupole ion trap with a synchrotron radiation VUV ...
Canon, Francis +5 more
core +3 more sources

