Results 31 to 40 of about 79,525 (194)

Neuroprotective and neuroregenerative potential of pharmacologically-induced hypothermia with D-alanine D-leucine enkephalin in brain injury

Neural Regeneration Research, 2018
Neurovascular disorders, such as traumatic brain injury and stroke, persist as leading causes of death and disability – thus, the search for novel therapeutic approaches for these disorders continues.
M Grant Liska, Marci G Crowley, Julian P Tuazon, Cesar V Borlongan   +3 more
doaj   +1 more source

Light microscopic immunocytochemical identification of leucine enkephalin [PDF]

, 2015
Leucine-enkephalin is a potent and naturally-occurring opioid peptide which serves to inhibit other neurotransmitters involved with pain perception, thereby reducing its emotional and physical impact.
Minkov, Minko; Medical university of Varna, Hristov, Stanislav; Medical university of Sofia, Malinova, Lina G.; Medical university of Sofia, Ovtscharoff, Wladimir A.; Medical university of Sofia, Alexandrov, Alexandar; Medical university of Sofia, Hinova-Palova, Dimka V.; Medical university of Sofia, Edelstein, Lawrence; Medimark corp., San Diego, CA, Paloff, Adrian M.; Medical university of Varna, Landzhov, Boycho V.; Medical university of Sofia   +8 more
core   +1 more source

Metal-Binding Ability of Leu-Enkephalin, Related Glycoconjugates and Peptidomimetics

Croatica Chemica Acta, 2015
Both the chemistry and consequences of the nonenzymatic reaction between reducing sugars and reactive amino groups of amino acids, peptides and proteins (known as the Maillard reaction), have received considerable attention in food and health science ...
Zsuzsa Majer, Elemér Vass, Maja Roščić, Miklós Hollósi, Štefica Horvat, Andreja Jakas   +5 more
doaj   +1 more source

An Immunocytochemical Study of Endocrine Cells in the Gut of a Stomachless Teleost Fish, Grass Carp, Cyprinidae

Cell Transplantation, 1993
Nineteen different antisera raised against mammalian hormones were used to identify the occurrence and distribution of endocrine cells in the gut of grass carp (Ctenopharyngodon idellus).
Qian-Sheng Pan, Zhi-Ping Fang
doaj   +1 more source

Kinetics of chymotrypsin- and papain-catalysed synthesis of [leucine]enkephalin and [methionine]enkephalin [PDF]

Biochemical Journal, 1984
The proteinase-catalysed synthesis of [Leu]enkephalin and [Met]enkephalin was studied kinetically. N alpha-t-Butoxycarbonyl-amino acids and peptides or their ethyl esters served as acyl donors, and amino acid phenylhydrazides were used as acyl acceptors.
openaire   +3 more sources

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

Clinical trial of electroacupuncture at Neimadian-point for cancer pain

针刺研究, 2020
Objective To observe the clinical efficacy and safety of electroacupuncture(EA) at Neimadian-point for cancer pain. Methods A total of 140 cancer patients with pain were randomly divided into EA and control groups, with 70 cases in each group.
HAN Xue-chang, XING Qun-zhi, LI Yu, DONG Xu, MA Xiao-wu, ZHANG Lu, WANG Qian-qian   +6 more
doaj  

Unravelling the Intraspecific Variation in Drought Responses in Seedlings of European Black Pine (Pinus Nigra J.F. Arnold)

Plant, Cell &Environment, EarlyView.
ABSTRACT Understanding intraspecific variation in drought tolerance is essential for predicting the adaptive capacity of forest species under climate change. Yet, the molecular basis of this variation remains poorly understood in ecologically and economically important conifers.
Muhammad Ahmad, Almuth Hammerbacher, Clara Priemer, Albert Ciceu, Marta Karolak, Sonja Mader, Sanna Olsson, Johann Schinnerl, Sebastian Seitner, Selina Schöndorfer, Paula Helfenbein, Jakub Jez, Michaela Breuer, Ana Espinosa‐Ruiz, Teresa Caballero, Andrea Ganthaler, Stefan Mayr, Dominik K. Großkinsky, Stefanie Wienkoop, Silvio Schueler, Carlos Trujillo‐Moya, Marcela van Loo   +21 more
wiley   +1 more source

Antinociceptive Effect of Intrathecal Injection of Genetically Engineered Human Bone Marrow Stem Cells Expressing the Human Proenkephalin Gene in a Rat Model of Bone Cancer Pain

Pain Research and Management, 2017
Background. This study aimed to investigate the use of human bone marrow mesenchymal stem cells (hBMSCs) genetically engineered with the human proenkephalin (hPPE) gene to treat bone cancer pain (BCP) in a rat model. Methods. Primary cultured hBMSCs were
Yi Sun, Yuke Tian, Haifeng Li, Dengwen Zhang, Qiang Sun   +4 more
doaj   +1 more source

Valorization of Zingiber officinale Roscoe leaf biomass: phytotoxic potential and chemical profiling toward sustainable weed management

Journal of the Science of Food and Agriculture, Volume 106, Issue 13, Page 8189-8201, October 2026.
Abstract BACKGROUND Zingiber officinale Roscoe is widely cultivated as a spice and functional food, generating substantial amounts of aerial biomass that is commonly discarded after harvest. Within a circular‐economy framework, this study investigated the phytotoxic potential of Z.
Sara Vitalini, Orlando Innaurato, Shadab Faramarzi, Alessandro Palmioli, Stefania Garzoli, Valentina Vaglia, Cristina Airoldi, Marcello Iriti   +7 more
wiley   +1 more source