Met-enkephalin-induced mobilization of intracellular Ca2+ in rat intracardiac ganglion neurones [PDF]
, 1999 The effects of Met-enkephalin on Ca2+-dependent K+ channel activity were investigated using the cell-attached patch recording technique on isolated parasympathetic neurones of rat intracardiac ganglia. Large-conductance, Ca2+-dependent K+ channels (BKCa)
Adams +18 more
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Birth Defects Research, Volume 117, Issue 11, November 2025.ABSTRACT Background Quaternary ammonium compounds (QACs) are common chemicals used for their antimicrobial, antistatic, and surfactant properties. Two common QACs, alkyldimethylbenzyl ammonium chloride (ADBAC or BAC) and didecyldimethyl ammonium chloride (DDAC), cause neural tube defects (NTDs) in mice and are proinflammatory in both mice and humans ...
Justin Kula +6 more
wiley +1 more source
MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys [PDF]
, 2012 MDAN-21, , a bivalent opioid ligand containing a mu-opioid receptor agonist (derived from oxymorphone) linked to the delta-opioid receptor antagonist (related to naltrindole) by a spacer of 21 atoms, was reported to have potent analgesic properties in ...
Aceto, Mario D. +6 more
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Chemistry &Biodiversity, Volume 22, Issue 11, November 2025.ABSTRACT Maize is an important crop worldwide with approximately 1200 million tons consumed and a market size worth $143 billion. Environmental stress influence production of crops and mitigating these ensures optimum production. Dicarboxylic acids are known as emulsifying agents that mitigate various stresses in plants.
Mhlonipheni Msomi +3 more
wiley +1 more source
World Journal of Acupuncture - MoxibustionObjectives: Retinal ischemia-reperfusion (RIR) injury results in irreversible visual impairments. The disruption of the outer blood-retinal barrier (OBRB) is a major ocular pathogenic process that RIR injury affects.
Ping CHEN +7 more
doaj +1 more source
Importance of MS selectivity and chromatographic separation in LC-MS/MS-based methods when investigating pharmaceutical metabolites in water. Dipyrone as a case of study. [PDF]
, 2012 Pharmaceuticals are emerging contaminants of increasing concern because of their presence in the aquatic environment and potential to reach drinking-water sources.
GRACIA LOR, EMMA +3 more
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Chemistry &Biodiversity, Volume 22, Issue 10, October 2025.Endophytic fungi of P. auritum were evaluated for their ability to produce inhibitors of formation of advanced glycation end products (AGEs). Neopestalotiopsis sp. H2 and Diaporthe sp. H5 extracts were the most active. So, we performed their chemical profiling by untargeted and phenolics‐targeted metabolomic approaches to identify the potential ...
Lory Sthephany Rochín‐Hernández +3 more
wiley +1 more source
Updating the list of known opioids through identification and characterization of the new opioid derivative 3,4-dichloro-N- (2-(diethylamino)cyclohexyl)-N- methylbenzamide (U-49900) [PDF]
, 2017 New psychoactive substances have been rapidly growing in popularity in the drug market as non-illegal drugs. In the last few years, an increment has been reported on the use of synthetic alternatives to heroin, the synthetic opioids.
Carbón, X. +7 more
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A Fast and Precise Method To Identify Indolic Glucosinolates and Camalexin in Plants by Combining Mass Spectrometric and Biological Information [PDF]
, 2012 In this manuscript, a fast and accurate identification and quantitation by mass spectrometry of indolic glucosinolates and camalexin involved in defense in Arabidopsis thaliana are described.
Arbona, Vicent, Gomez-Cadenas, Aurelio
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Studies on the small neuropeptide: RPCH and ENK, their function of reproductive regulation in the mud crab, Scylla paramamosain (Estampador, 1949) [PDF]
, 2013 拟穴青蟹（Scyllaparamamosain）是我国东南沿海重要的经济蟹类。本文以拟穴青蟹为研究对象，采用动物生理学、分子生物学、生物信息学等方法和手段，研究了3种小分子神经肽即红色素聚集激素（Redpigmentconcentratinghormone，RPCH）、亮氨酸-脑啡肽（Leucineenkephalin，Leu-ENK）和甲硫氨酸-脑啡肽（Methionineenkephalin，Met-ENK）的结构、特征和生殖调控功能。主要结果如下： （1 ...
曾慧
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