Objectives: Retinal ischemia-reperfusion (RIR) injury results in irreversible visual impairments. The disruption of the outer blood-retinal barrier (OBRB) is a major ocular pathogenic process that RIR injury affects.
Ping CHEN +7 more
doaj +1 more source
Studies on the small neuropeptide: RPCH and ENK, their function of reproductive regulation in the mud crab, Scylla paramamosain (Estampador, 1949) [PDF]
拟穴青蟹(Scyllaparamamosain)是我国东南沿海重要的经济蟹类。本文以拟穴青蟹为研究对象,采用动物生理学、分子生物学、生物信息学等方法和手段,研究了3种小分子神经肽即红色素聚集激素(Redpigmentconcentratinghormone,RPCH)、亮氨酸-脑啡肽(Leucineenkephalin,Leu-ENK)和甲硫氨酸-脑啡肽(Methionineenkephalin,Met-ENK)的结构、特征和生殖调控功能。主要结果如下: (1 ...
曾慧
core
A Fast and Precise Method To Identify Indolic Glucosinolates and Camalexin in Plants by Combining Mass Spectrometric and Biological Information [PDF]
In this manuscript, a fast and accurate identification and quantitation by mass spectrometry of indolic glucosinolates and camalexin involved in defense in Arabidopsis thaliana are described.
Arbona, Vicent, Gomez-Cadenas, Aurelio
core +2 more sources
Heavy metal stress induced the secretion of metabolites not secreted by non‐stressed microbiota. Heavy metal‐stressed microbiota secrete metabolites that inhibit XDR pathogens effectively. UPLC LC–MS tentatively identified novel metabolites, Tolyposamine and Gentiatibetine.
Kylah B. Millard +4 more
wiley +1 more source
Synthesis, biological evaluation, and utility of fluorescent ligands targeting the μ-opioid receptor [PDF]
Fluorescently labeled ligands are useful pharmacological research tools for studying receptor localization, trafficking, and signaling processes via fluorescence imaging. They are also employed in fluorescent binding assays. This study is centered on the
Briddon, Stephen J. +6 more
core +4 more sources
Background Gegen Qinlian Decoction (GQD) is a classical traditional Chinese medicine (TCM) formula primarily utilized for treating gut disorders. GQD showed therapeutic effects on several diseases in clinical and animal studies by targeting gut microbes.
Yaqin Peng +13 more
doaj +1 more source
MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys [PDF]
MDAN-21, , a bivalent opioid ligand containing a mu-opioid receptor agonist (derived from oxymorphone) linked to the delta-opioid receptor antagonist (related to naltrindole) by a spacer of 21 atoms, was reported to have potent analgesic properties in ...
Aceto, Mario D. +6 more
core +4 more sources
Beef hydrolysis by Zyactinase™ enzymes : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University, Auckland, New Zealand. [PDF]
Protein hydrolysis is the term that applies to all possible ways of splitting proteins to produce products with lower molecular weight. There is a continuous search for novel products derived from waste materials.
Ahmad, Noriza Binti
core
Molecular Aspect of Annelid Neuroendocrine system
Hormonal processes along with enzymatic processing similar to that found in vertebrates occur in annelids. Amino acid sequence determination of annelids precursor gene products reveals the presence of the respective peptides that exhibit high sequence ...
Salzet, M.
core +1 more source
Oral naltrexone treatment for cholestatic pruritus: A double-blind, placebo-controlled study [PDF]
Background and Aims: The efficacy of currently available therapeutic agents for cholestatic pruritus is often disappointing. The aim of this study was to assess the antipruritic effect of naltrexone, an oral opiate receptor antagonist.
Bertolotti, M. (M.) +5 more
core +4 more sources

