Opioid peptides are critically involved in a variety of physiological functions necessary for adaptation and survival, and as such, understanding the precise actions of endogenous opioid peptides will aid in identification of potential therapeutic ...
S. E. Calhoun+4 more
semanticscholar +1 more source
On-line electrogeneration of copper-peptide complexes in microspray mass spectrometry [PDF]
The interaction of copper ions with peptides was investigated by electrospray mass spectrometry. Two electrospray micro-emitters were compared, the first one with a platinum electrode using a copper(II) electrolyte solution containing a peptide sample ...
Girault, Hubert, Prudent, Michel
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MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys [PDF]
MDAN-21, , a bivalent opioid ligand containing a mu-opioid receptor agonist (derived from oxymorphone) linked to the delta-opioid receptor antagonist (related to naltrindole) by a spacer of 21 atoms, was reported to have potent analgesic properties in ...
Aceto, Mario D.+6 more
core +4 more sources
Untargeted metabolomics approach for unraveling robust biomarkers of nutritional status in fasted gilthead sea bream (Sparus aurata) [PDF]
A metabolomic study has been performed to identify sensitive and robust biomarkers of malnutrition in farmed fish, using gilthead sea bream (Sparus aurata) as a model.
Calduch-Giner, Josep+6 more
core +3 more sources
Heterologous Expression and Purification of \u3cem\u3eVibrio proteolyticus (Aeromonas proteolytica)\u3c/em\u3e Aminopeptidase: A Rapid Protocol [PDF]
Metalloaminopeptidases (mAPs) are enzymes that are involved in HIV infectivity, tumor growth and metastasis, angiogenesis, and bacterial infection. Investigation of structure–function relationships in mAPs is a prerequisite to rational design of anti-mAP
Bennett, Brian, Hartley, Mariam
core +1 more source
Liquid Chromatography-Electrospray Linear Ion Trap Mass Spectrometry Analysis of Targeted Neuropeptides in Tac1-/- Mouse Spinal Cords Reveal Significant Lower Concentration of Opioid Peptides [PDF]
Tachykinin and opioid peptides play a central role in pain transmission, modulation and inhibition. The treatment of pain is very important in medicine and many studies using NK1 receptor antagonists failed to show significant analgesic effects in ...
Beaudry, Francis, Saidi, Mouna
core +1 more source
Synthesis of methionine-5-enkephalin [PDF]
Yu. P. Shvachkin+3 more
openaire +2 more sources
Improvements in separation of peptides using capillary electrophoresis [PDF]
In this review, various aspect concerning the resolution of capillary electrophoresis for nine standard peptides ( namely, bradykinin, bradykinin fragment 1-5, substance P, Arg-vasopressin, luteinizing hormone·releasing hormone (LHRH), bombesin ...
Mohd Nazri Hafiz Mohd Khairi
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Application of Ion-Molecule Reactions to Structure Characterization and Thermochemical Property Measurements [PDF]
This thesis explores several novel applications of gas-phase ion-molecule reactions to solve analytical problems. In all cases, the application of an ion-molecule reaction to solve a specific challenge is based on a thorough understanding of the ...
Lin, Mingxiang
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Aceite de oliva virgen y regulación hormonal de la presión arterial: una revisión del papel de los enzimas proteolíticos [PDF]
Numerosos estudios realizados en los últimos años, han puesto de manifiesto que los niveles elevados de grasa en la dieta están directamente relacionados con el desarrollo de diversas patologías, entre las que destacan enfermedades cardiovasculares ...
Arrazola Saniger, M.+5 more
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