Results 91 to 100 of about 18,114 (279)

Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)

ELECTROPHORESIS, Volume 47, Issue 1, Page 106-136, January 2026.
ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley   +1 more source

A novel and highly efficient purification procedure for native human dipeptidyl peptidase 3 from human blood cell lysate.

PLoS ONE, 2019
Dipeptidyl amino-peptidase 3 (DPP3) is an aminopeptidase involved in peptide degradation, including hormone peptides as angiotensin II and enkephalins. DPP3 plasma activity increases in septic patients and correlates with mortality risk.
Paul Kaufmann, Matthias Muenzner, Mandy Kästorf, Karine Santos, Tobias Hartmann, Anke Dienelt, Linda Rehfeld, Andreas Bergmann   +7 more
doaj   +1 more source

A comprehensive review of the pharmacodynamics, pharmacokinetics and clinical effects of the neutral endopeptidase inhibitor racecadotril

Frontiers in Pharmacology, 2012
Racecadotril, via its active metabolite thiorphan, is an inhibitor of the enzyme neutral endopeptidase (NEP, EC 3.4.24.11), thereby increasing exposure to NEP including enkephalins and atrial natriuretic peptide.
Marion eEberlin, Thomas eMück, Martin C Michel   +2 more
doaj   +1 more source

Lipidomic Comparison of Detergent‐Soluble and Detergent‐Resistant Lipid Domains Isolated From Rat Cerebellum and the Effect of Hypoxia–Ischemia Using UPLC‐HDMSE

Journal of Mass Spectrometry, Volume 61, Issue 1, January 2026.
ABSTRACT Hypoxic ischemic encephalopathy (HIE) due to insufficient oxygen or blood flow to the brain can result in inflammation, impaired neurodevelopment, or death. Changes to microdomain lipid composition may contribute to altered structure and function of key regulatory processes; however, knowledge regarding changes to membrane lipid composition ...
Samuel A. Krug, Min He, Ningfeng Tang, Cynthia Bearer, Maureen A. Kane   +4 more
wiley   +1 more source

Activité analgésique des lymphocytes T CD4+ effecteurs générés au cours de la réponse immunitaire adaptative [PDF]

, 2012
La sensation douloureuse est une caractéristique de la réponse inflammatoire qui accompagne les infections par des pathogènes ou les lésions tissulaires.
Boué, Jérôme
core  

Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]

, 2013
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Ferenczi, Szilamér, Kovács, Krisztina J., Milanes, Victoria M., Nunez, Cristina, Pintér-Kübler, Bernadett, Polyák, Ágnes, Zelei, Edina   +6 more
core   +2 more sources

Molecular basis of domain‐specific angiotensin I‐converting enzyme inhibition by the antihypertensive drugs enalaprilat, ramiprilat, trandolaprilat, quinaprilat and perindoprilat

The FEBS Journal, Volume 293, Issue 2, Page 475-491, January 2026.
Inhibition of angiotensin I‐converting enzyme is an effective strategy for the treatment of hypertension. However, the clinically available ACE inhibitors cause side effects due to nonselective inhibition of the two catalytic domains of ACE (nACE and cACE).
Kyle S. Gregory, Vinasha Ramasamy, Edward D. Sturrock, K. Ravi Acharya   +3 more
wiley   +1 more source

The role of enkephalins in the perioperative period in patients with oropharyngeal cancer

Сибирский онкологический журнал
Postoperative metabolic disorder, namely the development of protein-energy deficiency is one of the challenges in cancer surgery, especially in head and neck surgeries, which are considered the most traumatic. The development of protein-energy deficiency
D. N. Vasiliev, D. E. Kulbakin, E. L. Choynzonov, S. V. Avdeev, A. A. Lee, I. P. Puteev, A. V. Pak, A. V. Kushner   +7 more
doaj   +1 more source

NEUROTROPHIC EFFECTS OF ETIFOXINE

Неврология, нейропсихиатрия, психосоматика, 2016
Higher anxiety results in the decreased levels of various neurotrophic factors and enkephalins and in impaired production of proinflammatory cytokines. The anxiolytic etifoxine is used to treat anxiety states and adjustment disorders. Etifoxine modulates
I. Yu. Torshin, O. A. Gromova, V. A. Semenov, O. A. Limanova, I. V. Gogoleva   +4 more
doaj   +1 more source

Ovariectomy Alters Gene Expression of the Hippocampal Formation in Middle-Aged Rats [PDF]

, 2016
Ovarian hormones regulate the transcriptome of the hippocampus and modulate its functions. During 29 menopause, this complex signaling declines, leading to impaired learning and memory.
Hrabovszky, Erik, Kalló, Imre, Liposits, Zsolt, Solymosi, Norbert, Sárvári, Miklós   +4 more
core   +1 more source