Results 71 to 80 of about 10,153 (221)

The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis

open access: yesExperimental Physiology, EarlyView.
Abstract The present review aimed to investigate the effectiveness of aerobic exercise (AE) compared to other interventions in decreasing pain intensity and reducing disability in individuals with neck pain. A systematic review (SR) of randomized controlled trials was conducted. This SR was registered in PROSPERO (CRD42021231231).
Ana lzabela Sobral de Oliveira‐Souza   +9 more
wiley   +1 more source

High‐Throughput N‐Glycan Analysis by IR‐MALDESI With a 1.5‐kHz Pulsed Mid‐IR Laser

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 5, May 2026.
ABSTRACT Infrared matrix‐assisted laser desorption electrospray ionization (IR‐MALDESI) is a laser‐based, hybrid ionization source for mass spectrometry, enabling both mass spectrometry imaging (MSI) and high‐throughput screening (HTS). In this work, a 2.2‐ns, 2.72‐μm laser, operating at 1.5 kHz, was integrated into the IR‐MALDESI platform to evaluate ...
Seth M. Eisenberg   +5 more
wiley   +1 more source

Interactions of the opioid and cannabinoid systems in reward: Insights from knockout studies

open access: yesFrontiers in Pharmacology, 2015
The opioid system consists of three receptors, mu, delta, and kappa, which are activated by endogenous opioid peptides (enkephalins, endorphins and dynorphins). The endogenous cannabinoid system comprises lipid neuromodulators (endocannabinoids), enzymes
Katia eBefort
doaj   +1 more source

Racecadotril for acute diarrhoea in children: systematic review and meta-analyses [PDF]

open access: yes, 2015
OBJECTIVE Racecadotril is an antisecretory agent that can prevent fluid/electrolyte depletion from the bowel as a result of acute diarrhoea, without affecting intestinal motility. An up-to-date systematic review is indicated to summarise the evidence on
Alam   +31 more
core   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1727-1746, May 2026.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun   +2 more
wiley   +1 more source

Catalytic Autoxidation for Depolymerization of Multilayer Plastic Films

open access: yesChemSusChem, Volume 19, Issue 7, 14 April 2026.
Catalytic autoxidation using a Co/Mn/Br catalyst system depolymerizes diverse polymers in multilayer plastic films, generating oxygenated small molecules such as dicarboxylic acids. The method tolerates additives and disrupters and converts up to 48 mol% polymer carbon into soluble products, enabling chemical recycling of complex plastic waste ...
Ciaran W. Lahive   +16 more
wiley   +1 more source

Multifactorial Perspective for Greening Solid‐Phase Peptide Synthesis: Rigid Polyacrylate Macroporous Resin in Combination with Green Solvents

open access: yesChemSusChem, Volume 19, Issue 7, 14 April 2026.
A rigid, non‐swelling polyacrylate resin enables greener solid‐phase peptide synthesis by allowing various green solvents during the peptide synthesis and significantly reduced process mass intensity without compromising peptide synthesis efficiency/purity.
Sikabwe Noki   +9 more
wiley   +1 more source

Specific fluorogenic substrates for neprilysin (neutral endopeptidase, EC 3.4.24.11) which are highly resistant to serine- and metalloproteases [PDF]

open access: yes, 1997
Two intramolecularly quenched fluorogenic peptides containing o-aminobenzoyl (Abz) and ethylenediamine 2,4-dinitrophenyl (EDDnp) groups at amino- and carboxyl-terminal amino acid residues, Abz-DArg-Arg-Leu-EDDnp (Abz-DRRL-EDDnp) and Abz-DArg-Arg-Phe ...
Boileau, G.   +4 more
core   +4 more sources

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Naloxone inhibits and morphine potentiates. The adrenal steroidogenic response to ACTH [PDF]

open access: yes
The adrenal actions were stereospecific since neither the positve stereoisomer of morphine, nor that of naloxone, had any effect on the adrenal response to exogenous adrenocorticotrophic hormone (ACTH).
Heybach, J. P., Vernikos, J.
core   +1 more source

Home - About - Disclaimer - Privacy