Results 91 to 100 of about 10,240 (222)

Receptors of peptides as therapeutic targets in epilepsy research [PDF]

open access: yes, 2014
Neuropeptides are signaling molecules participating in the modulation of synaptic transmission. Neuropeptides are stored in dense core synaptic vesicles, the release of which requires profound excitation.
Dobolyi, A.   +5 more
core   +1 more source

A novel and highly efficient purification procedure for native human dipeptidyl peptidase 3 from human blood cell lysate.

open access: yesPLoS ONE, 2019
Dipeptidyl amino-peptidase 3 (DPP3) is an aminopeptidase involved in peptide degradation, including hormone peptides as angiotensin II and enkephalins. DPP3 plasma activity increases in septic patients and correlates with mortality risk.
Paul Kaufmann   +7 more
doaj   +1 more source

A comprehensive review of the pharmacodynamics, pharmacokinetics and clinical effects of the neutral endopeptidase inhibitor racecadotril

open access: yesFrontiers in Pharmacology, 2012
Racecadotril, via its active metabolite thiorphan, is an inhibitor of the enzyme neutral endopeptidase (NEP, EC 3.4.24.11), thereby increasing exposure to NEP including enkephalins and atrial natriuretic peptide.
Marion eEberlin   +2 more
doaj   +1 more source

NEUROTROPHIC EFFECTS OF ETIFOXINE

open access: yesНеврология, нейропсихиатрия, психосоматика, 2016
Higher anxiety results in the decreased levels of various neurotrophic factors and enkephalins and in impaired production of proinflammatory cytokines. The anxiolytic etifoxine is used to treat anxiety states and adjustment disorders. Etifoxine modulates
I. Yu. Torshin   +4 more
doaj   +1 more source

Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]

open access: yes, 2013
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Ferenczi, Szilamér   +6 more
core   +2 more sources

The role of enkephalins in the perioperative period in patients with oropharyngeal cancer

open access: yesСибирский онкологический журнал
Postoperative metabolic disorder, namely the development of protein-energy deficiency is one of the challenges in cancer surgery, especially in head and neck surgeries, which are considered the most traumatic. The development of protein-energy deficiency
D. N. Vasiliev   +7 more
doaj   +1 more source

Nicotine Effects and the Endogenous Opioid System

open access: yesJournal of Pharmacological Sciences, 2014
.: Nicotine (NIC) is an exogenous ligand of the nicotinic acetylcholine receptor (nAChR), and it influences various functions in the central nervous system. Systemic administration of NIC elicits the release of endogenous opioids (endorphins, enkephalins,
Shiroh Kishioka   +3 more
doaj   +1 more source

Activité analgésique des lymphocytes T CD4+ effecteurs générés au cours de la réponse immunitaire adaptative [PDF]

open access: yes, 2012
La sensation douloureuse est une caractéristique de la réponse inflammatoire qui accompagne les infections par des pathogènes ou les lésions tissulaires.
Boué, Jérôme
core  

Evaluation of Analgesic Activity of Newly Synthesized Phthalyl- tyrosyl-glycin Sodium

open access: yesIraqi Journal of Pharmaceutical Sciences, 2017
Alteration in the backbone structure of the endogenously released opioid peptides Leu5/Met5 enkephalins may result in compounds having comparable profile of pharmacological activity but with different physicochemical properties and side effects. Phthalyl
Muthanna S. AL-Taee   +2 more
doaj   +1 more source

Capillary HPLC Separation of Selected Neuropeptides [PDF]

open access: yes, 2012
Neuropeptides play a pivotal role in brain and peripheral nervous system function. As high performance liquid chromatography (HPLC) becomes the central tool in the separation and characterization of peptide and protein samples, its selectivity ...
Yi, Ying
core  

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