Results 61 to 70 of about 6,613 (165)
Journal of the Science of Food and Agriculture, Volume 106, Issue 13, Page 8189-8201, October 2026.Abstract BACKGROUND Zingiber officinale Roscoe is widely cultivated as a spice and functional food, generating substantial amounts of aerial biomass that is commonly discarded after harvest. Within a circular‐economy framework, this study investigated the phytotoxic potential of Z.
Sara Vitalini +7 more
wiley +1 more source
Neurobiology of Disease, 2020 Neuropeptides are important signalling molecules in the brain and alterations in their expression levels have been linked to neurological disorders such as Parkinson's disease. It is challenging to map neuropeptide changes across and within brain regions
Heather Hulme +10 more
doaj +1 more source
Soybean induced resistance to Spodoptera eridania herbivory
Pest Management Science, Volume 82, Issue 10, Page 9931-9943, October 2026.SOD, CAT, APX, PPO, KTI, and MDA levels were higher in the resistant soybean. S. eridania herbivory increased H2O2 and MDA, but decreased SOD and PPO levels. S. eridania herbivory increased KTI activity only in the resistant variety. Isoquercitrin and daidzin were exclusive to resistant and susceptible soybeans.
Bruno Henrique Sardinha de Souza +6 more
wiley +1 more source
Archiv der Pharmazie, Volume 359, Issue 9, September 2026.We screened acrylamide bioisosteres against KRasG12C and prioritized primary hits by their GSH reactivity, labeling efficiency and specificity. The most promising fragment was combined with a KRas‐binding scaffold. Covalent binding, inhibitory activity and selectivity were confirmed via MS, NMR, biochemical and cell viability assays.
Nikolett Péczka +11 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.A dry extract of Libidibia ferrea (DELF) exhibits a phenolic profile associated with antioxidant and anti‐inflammatory activities. Free radical scavenging is demonstrated against DPPH, hydroxyl, and superoxide radicals, together with reduced NO and IL‐6 production in BV2 microglial cells, highlighting DELF as a promising source of bioactive compounds ...
Francisco Cirineu das Chagas Neto +9 more
wiley +1 more source
Interactions of the opioid and cannabinoid systems in reward: Insights from knockout studies
Frontiers in Pharmacology, 2015 The opioid system consists of three receptors, mu, delta, and kappa, which are activated by endogenous opioid peptides (enkephalins, endorphins and dynorphins). The endogenous cannabinoid system comprises lipid neuromodulators (endocannabinoids), enzymes
Katia eBefort
doaj +1 more source
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.An ethanol extract of Duchesnea chrysantha attenuates UVB‐induced oxidative stress, cell death, and inflammatory responses in keratinocytes while modulating extracellular‐matrix‐related markers in keratinocytes and dermal fibroblasts. These protective effects are associated with reduced TAK1 activation and suppression of NF‐κB, AP‐1, and MAPK signaling,
Yerkyesh Khamit +12 more
wiley +1 more source
The enkephalins and opiates: structure-activity relations
, 1977 The X-ray structures of 9 ‘opiate’ drugs which exhibit a range of pharmacological activity have been examined in detail leading to the theory that one of the reasons why the enkephalins and related peptides possess morphine-like activity is because they ...
Alan S Horn, John R Rodgers
core +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.This study identified two metabolically distinct thrombus molecular subtypes in AIS: a lipid metabolism‐enriched subtype (C1) associated with cardioembolic stroke and poor functional outcomes, and a folate metabolism‐enriched subtype (C2) linked to atherothrombotic stroke and better prognosis. A six‐metabolite signature further demonstrated exploratory
Taoyuan Lu +7 more
wiley +1 more source
Cancer‐related pain: A bidirectional modulator of cancer progression
Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He +5 more
wiley +1 more source