Results 41 to 50 of about 6,613 (165)
Effects of enkephalins and two enzyme resistant analogues on monoamine synthesis and metabolism in rat brain [PDF]
, 1980 Methionine-enkephalin and leucineenkephalin, administered into the lateral ventricle of intact rats, increased the accumulation of DOPA by a naloxone-sensitive mechanism in different brain regions after inhibition of the aromatic l -amino acid ...
Carlsson, A. +2 more
core +1 more source
Effect of enkephalins on cardiac output and regional blood flow in conscious dogs
, 1989 Page H1656: C. L. Rosen, A. Cote, and G. G. Haddad. “Effect of enkephalins on cardiac output and regional blood flow in conscious dogs.” Figures 5 and 6 should appear as follows. (See PDF)
C. L. Rosen, A. Cote, G. G. Haddad
core +3 more sources
Anesthetic Mechanism of Myeloacupuncture in Joints аnd Spine Pathology
Bolʹ, Sustavy, Pozvonočnik, 2015 The article presents a literature review on the application of such method of reflexotherapy acupuncture as myeloacupuncture used in the pathology of the peripheral joints and spine.
V.V. Yakovlenko +2 more
doaj +1 more source
Gut Medicine, EarlyView.ABSTRACT Postoperative ileus (POI) is a frequent complication after surgical procedures, predominantly manifesting as aberrant gastrointestinal motility, which markedly extends the duration of postoperative recovery for patients. The clinical duration of POI is typically modulated by intricate inflammatory cascades, with mast cells assuming a critical ...
Tian‐le Zhang +4 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux +26 more
wiley +1 more source
The distribution and functions of the enkephalins.
, 1980 The enkephalins are two pentapeptides with pharmacological properties similar to narcotic drugs. These peptides are widely distributed in the central nervous system. The basal ganglia contain particularly high concentrations of enkaphalins.
V M Pickel, R J Miller
core +1 more source
Wellcome Open Research, 2018 Background: Functional deletion of the Scn9a (sodium voltage-gated channel alpha subunit 9) gene encoding sodium channel Nav1.7 makes humans and mice pain-free. Opioid signalling contributes to this analgesic state.
Vanessa Pereira +5 more
doaj +1 more source
The c‐Src inhibitor eCF506 diminishes opioid tolerance and reduces β‐arrestin2 recruitment
British Journal of Pharmacology, EarlyView.Morphine activation of μ receptors causes tolerance through c‐Src activation and β‐arrestin2 recruitment. c‐Src inhibition or degradation reduces β‐arrestin2 recruitment, μ receptor endocytosis, while causing receptor upregulation, all likely contributing to reduced morphine tolerance.
Samuel Singleton +6 more
wiley +1 more source
Hemorrhage alters plasma and cardiac enkephalins and catecholamines in anesthetized dogs
, 1995 Intrinsic cardiac enkephalins participate in circulatory regulation either through the modification of vagal control or vasomotor sympathetic control.
Z. Mateo +4 more
core +1 more source
Enkephalins: Endogenous Analgesics with an Emerging Role in Stress Resilience
Neural Plasticity, 2017 Psychological stress is a state of mental or emotional strain or tension that results from adverse or demanding circumstances. Chronic stress is well known to induce anxiety disorders and major depression; it is also considered a risk factor for ...
Mathilde S. Henry +3 more
doaj +1 more source