Results 31 to 40 of about 6,613 (165)
Challenges and new opportunities for detecting endogenous opioid peptides in reward
Addiction Neuroscience, 2022 The endogenous opioid peptide system, comprised of enkephalins, endorphins, dynorphins, and nociceptin, is a highly complex neurobiological system. Opioid peptides are derived from four precursor molecules and undergo several processing events yielding ...
Sineadh M. Conway +2 more
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δ and μ opiate receptor probes: fluorescent enkephalins with high receptor affinity and specificity [PDF]
, 1985 The fluorescent amino acid, L-1-pyrenylalanine (Pya) was incorporated into [D-Ala2,Leu5]enkephalin and its methyl ester at position 4 or 5. Pya-enkephalins showed strong fluorescent intensity and displayed high binding affinity for opiate receptors. Pya4-
Haruhiko Aoyagi +13 more
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Endogenous analgesia mediated by CD4+ T lymphocytes is dependent on enkephalins in mice [PDF]
, 2016 International audienceAbstractBackgroundT cell-derived opioids play a key role in the control of inflammatory pain. However, the nature of opioids produced by T cells is still matter of debate in mice.
Deraison, Céline +15 more
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Enkephalins and ACTH in the mammalian nervous system
, 2019 7 p.The pentapeptides methionine-enkephalin and leucine-enkephalin belong to the opioid family of peptides, and the non-opiate peptide adrenocorticotropin hormone (ACTH) to the melanocortin peptide family. Enkephalins/ACTH are derived from pro-enkephalin,
Rafael Coveñas +7 more
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THE PEROXIDASE-CATALYZED OXIDATION OF ENKEPHALINS
, 1991 In vitro experiments are reported showing that Leu-enkephalin and Met-enkephalin, in the presence of hydrogen peroxide, can be oxidized by horseradish peroxidase.
BLARZINO, Carla +4 more
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Isolation and structural characterization of enkephalins in the brain of the Rhynchobdellid leech Theromyzon tessulatum [PDF]
, 1995 This paper reports the purification of four peptides related to enkephalins from the brain of the leech Theromyzon tessulatum. After reverse-phase HPLC purification, the sequence of the enkephalins (YGGFM, YGGFL, FM, FL) was established by a combination ...
Verger-Bocquet, Martine +7 more
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Geroprotective properties of neuroprotective and neurotrophic peptides
Неврология, нейропсихиатрия, психосоматика, 2020 Objective: to elucidate whether cerebrolysin contains peptide fragments that promote geroprotection.Material and methods. The peptide composition of cerebrolysin underwent a comprehensive mass spectrometric analysis, followed by a systemic biological ...
O. A. Gromova +4 more
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Interaction of enkephalins with oxyradicals.
, 2000 Enkephalin Interaction with reactive oxygen species has been investigated. All the peptides tested exhibited hydroxyl radical and superoxide anion scavenging ability. Enkephalins undergo an oxidative modification by Fenton systems.
FONTANA, Mario +5 more
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Frontiers in Immunology, 2022 Aminopeptidase N, or CD13, is a cell membrane ectopeptidase highly expressed in myeloid cells. Through its enzymatic activity, CD13 regulates the activity of several bioactive peptides, such as endorphins and enkephalins, chemotactic peptides like MCP-1 ...
Erandi Pérez-Figueroa +2 more
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Chromatographic behaviour and purification of N1.5-glycosyl enkephalins
, 1988 N1.5-Glycosyl enkephalins are potent analgesics. Two enkephalin-related glycosyl peptides: [DMet2, Pro5] enkephalin (N1.5 β-glucopyranosyl] amide and [DMet2, Pro5] enkephalin [N1.5 β-galactosyl] amide have been prepared following the liquid phase ...
García-Antón, José María +5 more
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