Nicotine Effects and the Endogenous Opioid System
Journal of Pharmacological Sciences, 2014 .: Nicotine (NIC) is an exogenous ligand of the nicotinic acetylcholine receptor (nAChR), and it influences various functions in the central nervous system. Systemic administration of NIC elicits the release of endogenous opioids (endorphins, enkephalins,
Shiroh Kishioka +3 more
doaj +1 more source
Liquid Chromatography-Electrospray Linear Ion Trap Mass Spectrometry Analysis of Targeted Neuropeptides in Tac1-/- Mouse Spinal Cords Reveal Significant Lower Concentration of Opioid Peptides [PDF]
, 2015 Tachykinin and opioid peptides play a central role in pain transmission, modulation and inhibition. The treatment of pain is very important in medicine and many studies using NK1 receptor antagonists failed to show significant analgesic effects in ...
Beaudry, Francis, Saidi, Mouna
core +1 more source
Capillary HPLC Separation of Selected Neuropeptides [PDF]
, 2012 Neuropeptides play a pivotal role in brain and peripheral nervous system function. As high performance liquid chromatography (HPLC) becomes the central tool in the separation and characterization of peptide and protein samples, its selectivity ...
Yi, Ying
core
Toksikologija bioregulatora kao potencijalnih bioloških agensa [PDF]
, 2005 Bioregulators or modulators are biochemical compounds such as peptides, that occur naturally in organisms. Advances in biotechnology create the potential for the misuse of peptide bioregulators in offensive biological weapons programmes.
Slavko Bokan
core +1 more source
Frontiers in PharmacologyNeprilysin (NEP), a zinc-dependent membrane-bound metallopeptidase, regulates various bioactive peptides, particularly in kidneys, vascular endothelium, and the central nervous system.
Xinyue Zhang +5 more
doaj +1 more source
Effect of neonatal infraorbital nerve transection on substance P- and leucine enkephalin-like immunoreactivities in trigeminal subnucleus caudalis of the rat [PDF]
, 1988 RW Rhoades +3 more
openalex +1 more source
THE EFFECT OF DZIKIR CONCERNING TO PAIN LEVEL AFTER SURGICAL OPERATION REDUCTION INTERNAL FIXATION (ORIF) [PDF]
, 2015 Background: Surgical operation of ORIF affect painful which disturb the patient’s comfortable. Dzikir have psychological benefit psichologis which affect comfortable and spiritual feelings focused to Allah, so could give a relaxation effect to percepts ...
Misnawati, Wiwik +1 more
core
VIP-, substance P- and met-enkephalin-immunoreactive innervation of the human gastroduodenal mucosa and Brunner's glands. [PDF]
, 1984 Gian‐Luca Ferri +7 more
openalex +1 more source
A novel non-Opioid binding site for endomorphin-1 [PDF]
, 2016 Endomorphins are natural amidated opioid tetrapeptides with the following structure: Tyr-Pro-Trp-Phe-NH2 (endomorphin-1),and Tyr-Pro-Phe-Phe-NH2 (endomorphin-2).
Benyhe, S. +8 more
core
Structure determination from powder data of two sub-peptides of Leu-enkephalin [PDF]
, 2005 Andrew N. Fitch, Luca Palin
openalex +1 more source