Results 201 to 210 of about 92,487 (246)

Short‐Chain Fatty Acids: Microbial Metabolites Driving Gut‐Eye Axis Signaling

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Short‐chain fatty acids generated by gut microbial fermentation link diet to ocular physiology via the gut–eye axis. Through systemic distribution, these metabolites regulate GPCR signaling, epigenetic pathways, inflammation, and angiogenesis, shaping retinal homeostasis and highlighting therapeutic potential in ocular vascular and inflammatory ...
Aleah J. Brokemond, Ronny Amamoo, Fapianey J. Alexandre, Sewedo B. Ajisegiri, Menaka C. Thounaojam, Pamela M. Martin, Ravirajsinh N. Jadeja   +6 more
wiley   +1 more source

Endothelial Dysfunction and Obesity: New Diagnostic and Therapeutic Strategies. [PDF]

Int J Mol Sci
Giglio RV, Stankovic S, Patti AM, Rizzo M, Ciaccio M.   +4 more
europepmc   +1 more source

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source

Determinants of graft patency after coronary artery bypass grafting. [PDF]

Front Cardiovasc Med
Ti HH, Gao SB, Wu YT, Dong SJ.
europepmc   +1 more source

Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework

Journal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah, Alaa Abdelhamid, Omar Tluli, Yaman Al‐Haneedi, Mera Abu Hussien, Ali H. Eid   +5 more
wiley   +1 more source

Quantitative characterization of L-citrulline as a precursor of L-arginine in rats: pharmacokinetic basis for nitric oxide-mediated effects. [PDF]

Front Pharmacol
Song S, Thapa SK, Upadhyay M, Yang S, Kim T, Yoo SD, Shin BS, Shin S.   +7 more
europepmc   +1 more source

Shear Stress‐Stimulated Trafficking of Endothelial Piezo1 to Splenic Capsule Boosts Spleen Contraction and Exercise Endurance

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
The vasculo‐splenic axis during exercise: shear stress triggers the release of medium/large extracellular vesicles from vascular endothelial cells via activation of Piezo1, shuttling Piezo1 to the smooth muscle cells in the splenic capsule; the translocated Piezo1 within the splenic capsule acts as a downstream effector of the α1‐adrenergic receptor ...
Jing Lou, Mingzong Yang, Yang Hu, Xuyun Liu, Han Li, Zihang Feng, Yuxin Xi, Changyang Xing, Lijun Yuan, Jia Li, Shengpeng Wang, Feng Gao, Xing Zhang   +12 more
wiley   +1 more source

Glucagon-like peptide-1-based therapies and the intersection of metabolic and skin disease. [PDF]

JAAD Case Rep
Ormaza-Vera A, Enos CW.
europepmc   +1 more source

Expert Consensus Statement: Committee on Implantable Devices and Committee on Social Issues, Japanese Heart Rhythm Society (JHRS) Statement on Remote Monitoring of Cardiac Implantable Electronic Devices

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
This statement of the Japanese Heart Rhythm Society (JHRS) provides comprehensive guidance for medical professionals and device manufacturers involved in RM. ABSTRACT Remote monitoring (RM) has been established as a standard tool for the management of patients with cardiac implantable electronic devices (CIEDs), offering advantages such as early event ...
Eiichi Watanabe, Nobuhiro Nishii, Akiko Maeda, Yoshiro Sakai, Katsuhito Fujiu, Makoto Suzuki, Ritsushi Kato, Haruhiko Abe, Takashi Noda, Hiroshi Tada, Masahiko Takagi   +10 more
wiley   +1 more source

Targeting Mitochondrial Dynamics in VEGFR-TKI Hypertension and Cardiotoxicity. [PDF]

Hypertension
Jankauskas SS, Kansakar U, Mone P, Pande S, Varzideh F, Santulli G.   +5 more
europepmc   +1 more source