Results 41 to 50 of about 1,893,563 (279)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

In-situ stress prediction methods for continental shale oil reservoirs based on rheological models

open access: yesShiyou shiyan dizhi
Continental shale oil reservoirs typically exhibit strong heterogeneity, high clay content, and complex structural configurations, which result in significant deviations in conventional in-situ stress prediction methods.
Xinyu WANG   +7 more
doaj   +1 more source

Volume fracturing of deep shale gas horizontal wells

open access: yesNatural Gas Industry B, 2017
Deep shale gas reservoirs buried underground with depth being more than 3500 m are characterized by high in-situ stress, large horizontal stress difference, complex distribution of bedding and natural cracks, and strong rock plasticity.
Tingxue Jiang   +6 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

BIM semantic-enrichment for built heritage representation [PDF]

open access: yes, 2018
In the built heritage context, BIM has shown difficulties in representing and managing the large and complex knowledge related to non-geometrical aspects of the heritage.
Acierno, Marta   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Elastic Reverse Time Migration for Weakly Illuminated Structure

open access: yesApplied Sciences, 2022
One of the most effective techniques to obtain PP and PS images is elastic reverse time migration which employs multi-component seismic data. The two types of complementary images play an important role in reducing blind spots in seismic exploration ...
Liwei Song   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Content enrichment through dynamic annotation [PDF]

open access: yes, 2004
This paper describes a technique for interceding between users and the information that they browse. This facility, that we term 'dynamic annotation', affords a means of editing Web page content 'on-the-fly' between the source Web server and the ...
Lepouras, George   +2 more
core  

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