Results 81 to 90 of about 1,893,563 (279)

Characterization of shale gas enrichment in the Wufeng Formation–Longmaxi Formation in the Sichuan Basin of China and evaluation of its geological construction–transformation evolution sequence

Journal of Natural Gas Geoscience, 2017
Shale gas in Upper Ordovician Wufeng Formation–Lower Silurian Longmaxi Formation in the Sichuan Basin is one of the key strata being explored and developed in China, where shale gas reservoirs have been found in Fuling, Weiyuan, Changning and Zhaotong ...
Zhiliang He, Zongquan Hu, Haikuan Nie, Shuangjian Li, Jin Xu   +4 more
doaj   +1 more source

Kinetics of Surface Enrichment: A Molecular Dynamics Study [PDF]

, 2010
We use molecular dynamics (MD) to study the kinetics of surface enrichment (SE) in a stable homogeneous mixture (AB), placed in contact with a surface which preferentially attracts A. The SE profiles show a characteristic double-exponential behavior with
Allen M. P., Binder K., Blakely J. M., Krausch G., Lipatov Y. S., Prabhat K. Jaiswal, Sanjay Puri, Subir K. Das, Young T.   +8 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Geochemical characteristics and their implication of light hydrocarbons in natural gas from the Lower Paleozoic carbonate reservoirs in the Daniudi gas field, Ordos Basin

Energy Exploration & Exploitation
The genetic types and source of the Lower Paleozoic natural gas in the Ordos Basin in China are controversial, and the geochemical characteristics of light hydrocarbons of natural gas in the fifth member of the Ordovician Majiagou Formation (O 1 m 5 ...
Xiaoqi Wu, Ping Wang, Chunhua Ni, Yingbin Chen, Jianhui Zhu   +4 more
doaj   +1 more source

Origin and carbon isotope reversal of shale gas in Wufeng-Longmaxi formations, Sichuan Basin: implication from pyrolysis experiments

Shiyou shiyan dizhi, 2020
The Wufeng-Longmaxi shale in the Sichuan Basin is the only stratum in China to realize commercial development of shale gas. There are some differences in shale gas generation and a lack of direct experimental evidence of the reasons for these differences.
Zhongliang MA, Baojian SHEN, Anyang PAN, Tenger BORJIGIN, Chuanxiang NING, Lunju ZHENG   +5 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Modes of occurrence and influencing factors of lithium in Li-rich coal from the Jungar coalfield, China, insights of LA-ICP-MS

International Journal of Coal Science & Technology
Due to the limitations of widely used energy spectrum and spectral analyses for the determination of trace elements in coal, the modes of occurrence of Li still remains unclear.
Huidi Hao, Bo Jiu, Wenhui Huang, Mingzhe Sun   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Research on lower limit of TOC content for hydrocarbon expulsion and shale oil enrichment using carbon mass balance method: a case study of shale of lower submember of the third member of Paleogene Shahejie Formation in Jiyang Depression

Shiyou shiyan dizhi
Currently, research methods for determining the lower limit of total organic carbon (TOC) content for hydrocarbon expulsion from source rocks and for shale oil enrichment vary, and the determined lower limit values show significant differences.
Youshu BAO, Maowen LI, Zhengwei FANG, Lianbo WU, Dayang WANG, Yifei JIA   +5 more
doaj   +1 more source