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Enteric Neurospheres Are Not Specific to Neural Crest Cultures: Implications for Neural Stem Cell Therapies [PDF]

open access: yes, 2015
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
A Barlow   +61 more
core   +11 more sources

Analysis of enteric nervous system and intestinal epithelial barrier to predict complications in Hirschsprung’s disease

open access: yesScientific Reports, 2020
In Hirschsprung’s disease (HSCR), postoperative course remains unpredictable. Our aim was to define predictive factors of the main postoperative complications: obstructive symptoms (OS) and Hirschsprung-associated enterocolitis (HAEC).
Anne Dariel   +28 more
doaj   +1 more source

The Baseline Structure of the Enteric Nervous System and Its Role in Parkinson’s Disease

open access: yesLife, 2021
The gastrointestinal (GI) tract is provided with a peculiar nervous network, known as the enteric nervous system (ENS), which is dedicated to the fine control of digestive functions.
G. Natale   +5 more
semanticscholar   +1 more source

Parkinson mice show functional and molecular changes in the gut long before motoric disease onset

open access: yesMolecular Neurodegeneration, 2021
Background There is increasing evidence that Parkinson’s disease (PD) might start in the gut, thus involving and compromising also the enteric nervous system (ENS). At the clinical onset of the disease the majority of dopaminergic neurons in the midbrain
Manuela Gries   +22 more
doaj   +1 more source

Toll-Like Receptor 4 Modulates Small Intestine Neuromuscular Function through Nitrergic and Purinergic Pathways [PDF]

open access: yes, 2017
Objective: Toll-like receptors (TLRs) play a pivotal role in the homeostatic microflora-host crosstalk. TLR4-mediated modulation of both motility and enteric neuronal survival has been reported mainly for colon with limited information on the role of ...
Cecilia Giulivi   +12 more
core   +7 more sources

Ancient evolutionary origin of vertebrate enteric neurons from trunk-derived neural crest [PDF]

open access: yes, 2017
The enteric nervous system of jawed vertebrates arises primarily from vagal neural crest cells that migrate to the foregut and subsequently colonize and innervate the entire gastrointestinal tract.
A Peters   +30 more
core   +2 more sources

The enteric nervous system

open access: yesDevelopmental Biology, 2012
The enteric nervous system (ENS), the intrinsic innervation of the gastrointestinal tract, consists of numerous types of neurons, and glial cells, that are distributed in two intramuscular plexuses that extend along the entire length of the gut and control co-ordinated smooth muscle contractile activity and other gut functions.
Sasselli, Valentina   +2 more
openaire   +2 more sources

Maternal prebiotic supplementation impacts colitis development in offspring mice

open access: yesFrontiers in Nutrition, 2023
Background and aimsMaternal diet plays a key role in preventing or contributing to the development of chronic diseases, such as obesity, allergy, and brain disorders.
Amélie Lê   +12 more
doaj   +1 more source

Functional circuits and signal processing in the enteric nervous system

open access: yesCellular and Molecular Life Sciences, 2020
The enteric nervous system (ENS) is an extensive network comprising millions of neurons and glial cells contained within the wall of the gastrointestinal tract.
C. Fung, P. Vanden Berghe
semanticscholar   +1 more source

Altered epithelial barrier functions in the colon of patients with spina bifida

open access: yesScientific Reports, 2022
Our objectives were to better characterize the colorectal function of patients with Spina Bifida (SB). Patients with SB and healthy volunteers (HVs) completed prospectively a standardized questionnaire, clinical evaluation, rectal barostat, colonoscopy ...
Charlène Brochard   +15 more
doaj   +1 more source

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