Results 41 to 50 of about 77,004 (325)

Intestinal neuromuscular function after preservation and transplantation [PDF]

, 1996
While it is well known that prolonged preservation of the intestinal graft causes severe mucosal damage after transplantation, little is known about the effect on neuromuscular function.
Hamada, N, Hutson, WR, Ikoma, A, Nakada, K, Starzl, TE, Suzuki, T, Todo, S, Zhu, Y   +7 more
core   +1 more source

The regulation of enteric neuron connectivity by semaphorin 5A is affected by the autism-associated S956G missense mutation

iScience
Summary: The neural network of the enteric nervous system (ENS) underlies gastrointestinal functions. However, the molecular mechanisms involved in enteric neuronal connectivity are poorly characterized. Here, we studied the role of semaphorin 5A (Sema5A)
Morgane E. Le Dréan, Catherine Le Berre-Scoul, Vincent Paillé, Martial Caillaud, Thibauld Oullier, Jacques Gonzales, Philippe Hulin, Michel Neunlist, Sophie Talon, Hélène Boudin   +9 more
doaj   +1 more source

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice [PDF]

, 2012
Pathological studies on Parkinson’s disease (PD) patients suggest that PD pathology progresses from the enteric nervous system (ENS) and the olfactory bulb into the central nervous system.
Arnhold, Mike, Funk, Richard H W, Gille, Gabriele, Marsico, Giovanni, O'Sullivan, Gregory A., Pal, Arun, Pan-Montojo, Francisco, Reichmann, Heinz, Rodrigo-Angulo, Margarita Lucía, Said, Jonas, Schwarz, Mathias, Verbavatz, Jean Marc, Winkler, Clemens   +12 more
core   +2 more sources

Extending the enteric nervous system

Biomedicine & Pharmacotherapy, 2007
The work reviews the evidence suggesting that lingual components of the autonomic system may be considered the most rostral portion of the enteric nervous system (ENS) defining the concept of lingual ENS (LENS). The LENS is not dissimilar from the more distally located portions of the ENS, however, it is characterized by a massive sensory input ...
SBARBATI, Andrea, OSCULATI, Francesco
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesisResearch in context

EBioMedicine, 2019
Background: Colon cancer stem cells (CSCs), considered responsible for tumor initiation and cancer relapse, are constantly exposed to regulatory cues emanating from neighboring cells present in the tumor microenvironment.
Simon Valès, Gregory Bacola, Mandy Biraud, Mélissa Touvron, Anne Bessard, Fanny Geraldo, Kelsie A. Dougherty, Shaian Lashani, Céline Bossard, Mathurin Flamant, Emilie Duchalais, Séverine Marionneau-Lambot, Thibauld Oullier, Lisa Oliver, Michel Neunlist, François M. Vallette, Laurianne Van Landeghem   +16 more
doaj   +1 more source

Anatomical and functional maturation of the mid-gestation human enteric nervous system

Nature Communications, 2023
Immature gastrointestinal motility impedes preterm infant survival. The enteric nervous system controls gastrointestinal motility, yet it is unknown when the human enteric nervous system matures enough to carry out vital functions.
Lori B. Dershowitz, Li Li, Anca M. Pasca, Julia A. Kaltschmidt   +3 more
doaj   +1 more source

Chronic Stress, Inflammation, and Colon Cancer: A CRH System-Driven Molecular Crosstalk. [PDF]

, 2019
Chronic stress is thought to be involved in the occurrence and progression of multiple diseases, via mechanisms that still remain largely unknown. Interestingly, key regulators of the stress response, such as members of the corticotropin-releasing ...
Baritaki, Stavroula, Chatzaki, Ekaterini, de Bree, Eelco, Pothoulakis, Charalabos   +3 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Mycotoxins and the Enteric Nervous System

Toxins, 2020
Mycotoxins are secondary metabolites produced by various fungal species. They are commonly found in a wide range of agricultural products. Mycotoxins contained in food enter living organisms and may have harmful effects on many internal organs and ...
Sławomir Gonkowski, Magdalena Gajęcka, Krystyna Makowska   +2 more
doaj   +1 more source