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Epidemiology and outcomes associated with MBL-producing Enterobacterales: A systematic literature review

International Journal of Antimicrobial Agents
The increasing prevalence of infections due to metallo-β-lactamase (MBL)-producing Enterobacterales poses a serious concern given the limited treatment options available.
, Francis F Arhin, Maria Gheorghe
exaly   +2 more sources

Gut Microbiome and Intestinal Colonization with Multidrug-Resistant Strains of Enterobacterales: An Interplay Between Microbial Communities

open access: yesAntibiotics
Background: The intestinal tract is a host to a high number of diverse bacteria, and the presence of multidrug-resistant (MDR) Enterobacterales strains acts as a reservoir and a source of infection.
Béla Kocsis, Dóra Szabó, Laszlo Sipos
semanticscholar   +2 more sources

Updates on the Virulence Factors Produced by Multidrug-Resistant Enterobacterales and Strategies to Control Their Infections [PDF]

open access: yesMicroorganisms, 2023
The Enterobacterales order is a massive group of Gram-negative bacteria comprised of pathogenic and nonpathogenic members, including beneficial commensal gut microbiota.
Mohd W Azam   +2 more
exaly   +3 more sources

Characteristics of community-acquired carbapenem-resistant Enterobacterales

Journal of Antimicrobial Chemotherapy, 2022
AbstractBackgroundCommunity-acquired carbapenem-resistant Enterobacterales (CA-CRE) are an important threat.MethodsIn CRACKLE-2, we defined patients with CA-CRE as admitted from home, without pre-existing conditions, and a positive culture within 48 h of admission.
Rima Shrestha   +73 more
openaire   +2 more sources

Therapeutic Options for Metallo-β-Lactamase-Producing Enterobacterales

open access: yesInfection and Drug Resistance, 2021
The spread of metallo-β-lactamase (MBL)-producing Enterobacterales worldwide without the simultaneous increase in active antibiotics makes these organisms an urgent public health threat. This review summarizes recent advancements in diagnostic and treatment strategies for infections caused by MBL-producing Enterobacterales.
Kimberly Baugh   +2 more
exaly   +6 more sources

The Potential of Probiotics to Eradicate Gut Carriage of Pathogenic or Antimicrobial-Resistant Enterobacterales

open access: yesAntibiotics, 2021
Probiotic supplements have been used to decrease the gut carriage of antimicrobial-resistant Enterobacterales through changes in the microbiota and metabolomes, nutrition competition, and the secretion of antimicrobial proteins.
Yuan-Pin Hung   +2 more
exaly   +2 more sources

Polymyxin resistance in Enterobacterales: overview and epidemiology in the Americas

International Journal of Antimicrobial Agents, 2021
The worldwide spread of carbapenem- and polymyxin-resistant Enterobacterales represents an urgent public-health threat. However, for most countries in the Americas, the available data are limited, although Latin America has been suggested as a silent spreading reservoir for isolates carrying plasmid-mediated polymyxin resistance mechanisms.
J. Rodríguez-Santiago   +3 more
openaire   +2 more sources

Rapid detection of Enterobacterales that produce carbapenemases

Diagnostic Microbiology and Infectious Disease, 2020
The rapid detection of carbapenemases among Enterobacterales in clinical laboratories is critical for management of patients, and infection prevention and control efforts.A study was designed to evaluate the performances of the RAPIDEC CARBA NP®, β-CARBA®, NG-Test CARBA 5®, modified carbapenem-inactivation method, and EDTA version (eCIM) assays against
Wilson W, Chan   +3 more
openaire   +2 more sources

Socioeconomic disparities in the prevalence of multidrug resistance in Enterobacterales

Infection Control & Hospital Epidemiology, 2023
AbstractWe examined the association between multidrug resistance and socioeconomic status (SES), analyzing microbiological and ZIP-code–level socioeconomic data. Using generalized linear models, we determined that multidrug resistance is significantly and persistently more prevalent in samples taken from patients residing in low-income ZIP codes versus
Dylan R. Brown   +4 more
openaire   +2 more sources

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