Results 251 to 260 of about 28,778 (289)

Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (SIMPLIFY): an open-label, multicentre, randomised trial.

Lancet. Infectious Diseases (Print)
BACKGROUND De-escalation from broad-spectrum to narrow-spectrum antibiotics is considered an important measure to reduce the selective pressure of antibiotics, but a scarcity of adequate evidence is a barrier to its implementation.
L. López-Cortés, M. Delgado-Valverde, Elisa Moreno-Mellado, Josune Goikoetxea Aguirre, Laura Guío Carrión, María José Blanco Vidal, L. L. López Soria, M. Pérez-Rodríguez, Lucía Martínez Lamas, F. Arnaiz de las Revillas, C. Armiñanzas, Carlos Ruiz de Alegría-Puig, Patricia Jiménez Aguilar, María del Carmen Martínez-Rubio, Carmen Sáez-Béjar, C. de las Cuevas, Andrés Martín-Aspas, Fátima Galán, José Ramón Yuste, José Leiva-León, G. Bou, Patricia Capón González, L. Boix-Palop, Mariona Xercavins-Valls, M. A. Goenaga-Sánchez, Diego Vicente Anza, J. Castón, Manuel Recio Rufián, Esperanza Merino, J. Rodríguez, Belén Loeches, G. Cuervo, J. G. Guerra Laso, Antonio Plata, Salvador Pérez Cortés, Pablo López Mato, José Luis Sierra Monzón, C. Rosso-Fernández, J. Bravo-Ferrer, P. Retamar-Gentil, Jesús Rodríguez-Baño   +40 more
semanticscholar   +1 more source

Carbapenemase-Producing Enterobacterales in Algeria: A Systematic Review

Microbial Drug Resistance, 2020
The dramatic increase in prevalence and clinical impact of infections caused by carbapenemase-producing Enterobacterales (CPE) are major and ongoing public health problems globally. The carbapenemase groups most commonly encountered include Klebsiella pneumoniae carbapenemase (KPC), New Delhi
Abdelaziz, Touati, Assia, Mairi
openaire   +2 more sources

Clinical outcomes in patients infected with ertapenem-only-resistant Enterobacterales versus multi-carbapenem-resistant Enterobacterales

Journal of Antimicrobial Chemotherapy
Abstract Background Use of anti-carbapenem-resistant Enterobacterales (anti-CRE) agents such as ceftazidime/avibactam has been associated with improved clinical outcome in cohorts that primarily include patients infected with CRE that are resistant to meropenem (MCRE).
Gregory Weston, Abhigya Giri, Lauren Komarow, Lizhao Ge, Keri R Baum, Erin Abbenante, Jason C Gallagher, Jesse T Jacob, Keith S Kaye, Angela C Kim, W Charles Huskins, Marcus Zervos, Erica Herc, Robin Patel, David Van Duin, Yohei Doi   +15 more
openaire   +2 more sources

Adverse Environmental Perturbations May Threaten Kelp Farming Sustainability by Exacerbating Enterobacterales Diseases.

Environmental Science and Technology
Globally kelp farming is gaining attention to mitigate land-use pressures and achieve carbon neutrality. However, the influence of environmental perturbations on kelp farming remains largely unknown.
Yongyu Zhang, Shailesh Nair, Zenghu Zhang, Jiulong Zhao, Hanshuang Zhao, Longfei Lu, Lirong Chang, Nianzhi Jiao   +7 more
semanticscholar   +1 more source

Hidden threats in the plastisphere: Carbapenemase-producing Enterobacterales colonizing microplastics in river water.

Science of the Total Environment
Carbapenem resistance poses a significant burden on healthcare systems worldwide. Microplastics (MPs) have emerged as potential contributors to antibiotic resistance spread in the environment.
Isabel Silva, M. Tacão, I. Henriques
semanticscholar   +1 more source

Resistencia a colistina en enterobacterales

2022
ABSTRACT Antimicrobial resistance currently represents one of the main public health problems worldwide. In our country, most nosocomial infections are caused by germs resistant to multiple antimicrobials. This situation has meant that in recent years colistin has been used for their treatment, the use of which has been limited for many years due to ...
openaire   +1 more source

Reviewing novel treatment options for carbapenem-resistant Enterobacterales

Expert Review of Anti-Infective Therapy
Introduction Carbapenem resistant Enterobacterales (CRE) are a major threat to global health and hospital-onset CRE infections have risen during the COVID-19 pandemic. Novel antimicrobials are now available for the treatment of CRE infections.
Natalie A. Mackow, D. van Duin
semanticscholar   +1 more source

Carbapenem-resistant Enterobacterales in the USA

The Lancet Infectious Diseases, 2020
Sumanth, Gandra, Carey-Ann D, Burnham
openaire   +2 more sources

Carriage and infections by multi-carbapenemases producing Enterobacterales

Diagnostic Microbiology and Infectious Disease
Multi-carbapenemases producing Enterobacterales (MCP-EB) represents a new public health challenge due to their ability to display complex resistance phenotypes.MCP-EB isolates identified from patients admitted to an Italian Center in the period 2020-2024 were included.
Matteo Boattini, Paulo Bastos, Cristina Costa, Gabriele Bianco   +3 more
openaire   +2 more sources

Carbapenem-resistant Enterobacterales (CRE): The storm is coming

Intensive and Critical Care Nursing, 2023
Zahar, Jean-Ralph, Blot, Stijn
openaire   +4 more sources