Tigecycline Treatment for Carbapenem-Resistant Enterobacteriaceae Infections: A Systematic Review and Meta-Analysis. [PDF]
Medicine (Baltimore), 2016 Carbapenem-resistant Enterobacteriaceae (CRE) infections are prevalent worldwide; they have few effective treatments and this jeopardizes public health.
Ni W +7 more
europepmc +2 more sources
Clinical outcomes of Enterobacteriaceae infections stratified by carbapenem MICs. [PDF]
J Clin Microbiol, 2015 ABSTRACT The Clinical and Laboratory Standards Institute (CLSI) lowered the MIC breakpoints for meropenem and imipenem from 4 mg/liter to 1 mg/liter for Enterobacteriaceae in 2010. The breakpoint change improves the probability of pharmacodynamic target attainment and eliminates the need for microbiology ...
Patel TS, Nagel JL.
europepmc +6 more sources
Carbapenem-Resistant Enterobacteriaceae Infections in Patients on Renal Replacement Therapy. [PDF]
Open Forum Infect Dis, 2017 Background Patients on chronic intermittent renal replacement therapy (RRT) are at risk for infection with carbapenem-resistant Enterobacteriaceae (CRE). However, the impact of RRT on outcomes after CRE infections remains to be defined. Here we perform a
Eilertson B +16 more
europepmc +2 more sources
Management of carbapenem-resistant Enterobacteriaceae infections. [PDF]
Clinical Microbiology and Infection, 2019 Carbapenem resistance is defined as in vitro non-susceptibility to any carbapenem and/or documented production of a carbapenemase. This feature has rapidly spread worldwide among clinical isolates of Enterobacteriaceae, mostly Klebsiella spp., and is associated with diverse molecular mechanisms. Carbapenem resistance is often associated with resistance
E. Durante-Mangoni +2 more
semanticscholar +5 more sources
Epidemiology of Carbapenem-Resistant Enterobacteriaceae Infections: Report from the China CRE Network. [PDF]
Antimicrob Agents Chemother, 2018 Zhang Y +30 more
europepmc +2 more sources
Present and Future of Carbapenem-resistant Enterobacteriaceae (CRE) Infections [PDF]
Antibiotics, 2019 Carbapenem-resistant Enterobacteriaceae (CRE) have become a public health threat worldwide. There are three major mechanisms by which Enterobacteriaceae become resistant to carbapenems: enzyme production, efflux pumps and porin mutations.
Beatriz Suay-García, M. Pérez-Gracia
semanticscholar +6 more sources
Multicenter Study of Outcomes with Ceftazidime-Avibactam in Patients with Carbapenem-Resistant Enterobacteriaceae Infections. [PDF]
Antimicrob Agents Chemother, 2017 King M +12 more
europepmc +2 more sources
Enterobacteriaceae infection – diagnosis, antibiotic resistance and prevention
Postępy Higieny i Medycyny Doświadczalnej, 2011 Intestinal infections caused by rod-shaped bacteria of the Enterobacteriaceae genus are one of the major health hazards in countries where sanitation standards are low. Strains of Shigella, Salmonella, Escherichia and Yersinia are responsible for diarrhea, severe bacillary dysentery, typhoid, other intestinal diseases, as well as genitourinary tract ...
Anna Jarząb +3 more
openalex +4 more sources
Pneumonia and Renal Replacement Therapy Are Risk Factors for Ceftazidime-Avibactam Treatment Failures and Resistance among Patients with Carbapenem-Resistant Enterobacteriaceae Infections [PDF]
Antimicrobial Agents and Chemotherapy, 2018 Ryan K. Shields +5 more
openalex +2 more sources
Beta-lactamases in Enterobacteriaceae infections in children. [PDF]
Journal of Infection, 2016 Multi-drug resistance in Gram negative bacteria, particularly in Enterobacteriaceae, is a major clinical and public health challenge. The main mechanism of resistance in Enterobacteriaceae is linked to the production of beta-lactamase hydrolysing enzymes such as extended spectrum beta-lactamases (ESBL), AmpC beta-lactamases and carbapenemases ...
C. Moxon, S. Paulus
semanticscholar +4 more sources