Results 81 to 90 of about 37,025 (171)
Intrinsic Disorder as a New Frontier in Antimicrobial Resistance and Bacterial Fitness
The works examines the link between intrinsic disorder in bacterial protein structure, and bacterial function, and antimicrobial resistance. It highlights how flexible, disordered proteins support secretion, stress responses, desiccation protection, and virulence, while also suggesting that these adaptable regions may provide novel targets for ...
Jack O' Callaghan +3 more
wiley +1 more source
Targeted faecal surveillance of conservation‐priority captive ungulates identified multidrug‐resistant nontyphoidal Salmonella and clinically relevant Enterococcus in a UAE urban zoo. These findings provide cross‐sectional baseline evidence supporting cautious integration of zoo‐based monitoring into One Health antimicrobial resistance surveillance ...
Ihab Habib +11 more
wiley +1 more source
Gut Microbiota‐Immune Associations in Community‐Dwelling Older Adults: Role of Polygonatum odoratum. ABSTRACT Aging is often associated with intestinal microbiota imbalance and immune system degeneration. The dysregulation and crosstalk of these two factors markedly elevate the elderly's susceptibility to infections and age‐related diseases ...
Tingting Xia +17 more
wiley +1 more source
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen +7 more
wiley +1 more source
Abstract This study evaluated the effects of dietary carbon‐to‐nitrogen (C/N) conditions, generated by combining Dunaliella salina with sugar beet raffinate, on the growth, survival, reproductive performance, biochemical composition, fatty‐acid profile, digestive enzyme activity, microbial community, and biomass production of Artemia parthenogenitica ...
Manizheh Biabani Asrami +2 more
wiley +1 more source
ABSTRACT Background & Aims Liver cirrhosis is associated with an increased risk of bacterial infections, but there is a lack of reliable population‐based data to quantify this risk. We examined the incidence and predictors of community‐acquired serious systemic infections.
Clara Juul Stenderup +4 more
wiley +1 more source
This review examines recent advances in integrating artificial intelligence (AI) with surface‐enhanced Raman spectroscopy (SERS) for the detection of pathogenic bacteria and evaluation of drug resistance phenotypes. Key challenges in clinical translation are critically discussed, along with prospective solutions and future research directions ...
Chen Liu +7 more
wiley +1 more source
Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai +7 more
wiley +1 more source
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen +9 more
wiley +1 more source
Halogeton sativus is investigated through phytochemical isolation, biological evaluation, molecular dicking, molecular dynamics simulation, and ADMET prediction. The identified metabolites exhibit promising antioxidant, anti‐inflammatory, antimicrobial, and antidiabetic activities, while computational analyses provide mechanistic insights and favorable
Abd Elbasset Tamersit +12 more
wiley +1 more source

