Results 71 to 80 of about 10,616,742 (287)

The role of mucosal immunity in the pathogenesis of necrotizing enterocolitis [PDF]

, 2017
Necrotizing enterocolitis (NEC) is the most devastating gastrointestinal disease of prematurity. Although the precise cause is not well understood, the main risk factors thought to contribute to NEC include prematurity, formula feeding, and bacterial ...
Bolock, Alexa M, Good, Misty, Hodzic, Zerina   +2 more
core   +2 more sources

High-fidelity Glucagon-CreER mouse line generated by CRISPR-Cas9 assisted gene targeting

Molecular Metabolism, 2017
Objective: α-cells are the second most prominent cell type in pancreatic islets and are responsible for producing glucagon to increase plasma glucose levels in times of fasting. α-cell dysfunction and inappropriate glucagon secretion occur in both type 1
Amanda M. Ackermann, Jia Zhang, Aryel Heller, Anna Briker, Klaus H. Kaestner   +4 more
doaj   +1 more source

Pink1 and Parkin regulate Drosophila intestinal stem cell proliferation during stress and aging. [PDF]

, 2017
Intestinal stem cells (ISCs) maintain the midgut epithelium in Drosophila melanogaster Proper cellular turnover and tissue function rely on tightly regulated rates of ISC division and appropriate differentiation of daughter cells.
Abramov, Amcheslavsky, Amcheslavsky, Amcheslavsky, Benard, Biteau, Biteau, Biteau, Buchon, Buchon, Buchon, Christopher L. Koehler, Clark, Clarkson, Coppé, Correia-Melo, D. Leanne Jones, Deng, Greene, Guo, Guy A. Perkins, Hackenbrock, Han, Henchcliffe, Hochmuth, Hur, Jiang, Jiang, Jones, Kashatus, Lee, Lee, Li, Liu, Maeda, Marianes, Mark H. Ellisman, McGuire, Micchelli, Myant, Nakamura, Nicholson, Ohlstein, Ohlstein, Osterwalder, O’Brien, Park, Passos, Poole, Poole, Rana, Rera, Resende, Resnik-Docampo, Roman, Springer, Sykiotis, Takashima, Tian, Twig, Wang, Wang, Wei, Westermann, Yang, Youle, Zeng, Zeng, Zhu   +68 more
core   +1 more source

Type 2 diabetes is associated with impaired jejunal enteroendocrine GLP-1 cell lineage in human obesity

International Journal of Obesity, 2020
Objectives Altered enteroendocrine cell (EEC) function in obesity and type 2 diabetes is not fully understood. Understanding the transcriptional program that controls EEC differentiation is important because some EEC types harbor significant therapeutic ...
Céline Osinski, L. le Gléau, C. Poitou, Juan de Toro-Martin, L. Genser, Magali Fradet, H. Soula, A. Leturque, C. Blugeon, Laurent Jourdren, Edwige-Ludiwyne Hubert, K. Clément, P. Serradas, A. Ribeiro   +13 more
semanticscholar   +1 more source

β-Lactoglobulin-linoleate complexes: In vitro digestion and the role of protein in fatty acids uptake [PDF]

, 2013
peer-reviewedThe dairy protein β-lactoglobulin (BLG) is known to bind fatty acids such as the salt of the essential longchain fatty acid linoleic acid (cis,cis-9,12-octadecadienoic acid, n-6, 18:2).
Bouhallab, Said, Brodkorb, Andre, Croguennec, Thomas, Giblin, Linda, Hennessy, Alan A., Le Maux, Solene   +5 more
core   +3 more sources

HISTOMORPHOLOGICAL STUDY OF ENDOCRINE CELLS IN VARIOUS REGION OF DIGESTIVE TRACT OF BUFFALO (BUBALUS BUBALIS) [PDF]

Exploratory Animal and Medical Research, 2014
The histomorphology of enteroendocrine cells were studied in different segments of gastrointestinal tract of six adult buffalo. Depending upon the histomorphological study, the enteroendocrine cells were divided into 7 different types viz.
S. Dehury, R.K. Das, U.K. Mishra, G.R. Sahoo, R. Patra   +4 more
doaj  

The Brain-Gut-Microbiome Axis. [PDF]

, 2018
Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-microbiome axis. Gut microbes communicate to the central nervous system through at least 3 parallel and interacting channels involving nervous, endocrine, and ...
Kalani, Amir, Martin, Clair R, Mayer, Emeran A, Osadchiy, Vadim   +3 more
core   +2 more sources

Characteristics of Enteroendocrine Cells of White Leghorn Chickens, Gallus gallus, Before and After Hatching

The Journal of Poultry Science, 2023
The aim of this study was to identify the histological features of chicken enteroendocrine cells before and after hatching. Tissue samples from the duodenum, proximal and distal parts of the jejunum and ileum, cecum and colorectum were collected from the
Md. Al amin, Md Salahuddin, Yuriko Imai, Kohzy Hiramatsu   +3 more
doaj   +1 more source

bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice [PDF]

, 2015
Helicobacter infection causes a chronic superficial gastritis that in some cases progresses via atrophic gastritis to adenocarcinoma. Proapoptotic bak has been shown to regulate radiation-induced apoptosis in the stomach and colon and also susceptibility
Abuderman, A A, Burkitt, M D, Duckworth, C A, O'Reilly, L A, Pritchard, D M, Williams, J M   +5 more
core   +2 more sources

Single-cell transcriptomic atlas of enteroendocrine cells along the murine gastrointestinal tract

PLoS ONE
Background Enteroendocrine cells (EECs) produce over 20 gut hormones which contribute to intestinal physiology, nutrient metabolism and the regulation of food intake. The objective of this study was to generate a comprehensive transcriptomic map of mouse
Christopher A Smith, Elisabeth A. A. O’Flaherty, Nunzio Guccio, Austin Punnoose, Tamana Darwish, Jo E Lewis, Rachel E. Foreman, Joyce Li, Richard G Kay, Alice E. Adriaenssens, F. Reimann, F. Gribble   +11 more
semanticscholar   +1 more source