Results 11 to 20 of about 4,441,967 (229)
Enteroendocrine Cells Support Intestinal Stem-Cell-Mediated Homeostasis in Drosophila [PDF]
Cell Reports, 2014 Summary: Intestinal stem cells in the adult Drosophila midgut are regulated by growth factors produced from the surrounding niche cells including enterocytes and visceral muscle. The role of the other major cell type, the secretory enteroendocrine cells,
Alla Amcheslavsky +7 more
doaj +8 more sources
Models and Tools for Studying Enteroendocrine Cells [PDF]
Endocrinology, 2018 AbstractGut hormones produced by gastrointestinal enteroendocrine cells modulate key physiological processes including glucose homeostasis and food intake, making them potential therapeutic candidates to treat obesity and diabetes. Understanding the function of enteroendocrine cells and the molecular mechanisms driving hormone production is a key step ...
Goldspink, Deborah A +2 more
openaire +5 more sources
Heterogeneous expression of Drosophila gustatory receptors in enteroendocrine cells. [PDF]
PLoS ONE, 2011 The gastrointestinal tract is emerging as a major site of chemosensation in mammalian studies. Enteroendocrine cells are chemosensory cells in the gut which produce regulatory peptides in response to luminal contents to regulate gut physiology, food ...
Jeong-Ho Park, Jae Young Kwon
doaj +2 more sources
Enteroendocrine cells and lipid absorption
Current Opinion in Lipidology, 2011 To examine recent papers linking enteroendocrine cells to lipid absorption.Specific inactivation of the proendocrine transcription factor neurogenin 3 (Ngn3) in the intestine leads to a loss of enteroendocrine cells, growth retardation, impaired lipid absorption and a high mortality during the weaning period.
Mellitzer, Georges, Gradwohl, Gerard
openaire +3 more sources
Enteroendocrine cells are specifically marked by cell surface expression of claudin-4 in mouse small intestine. [PDF]
PLoS ONE, 2014 Enteroendocrine cells are solitary epithelial cells scattered throughout the gastrointestinal tract and produce various types of hormones, constituting one of the largest endocrine systems in the body.
Takahiro Nagatake +3 more
doaj +2 more sources
Enteroendocrine cell types revisited
Current Opinion in Pharmacology, 2013 The GI-tract is profoundly involved in the control of metabolism through peptide hormones secreted from enteroendocrine cells scattered throughout the gut mucosa. A large number of recently generated transgenic reporter mice have allowed for direct characterization of biochemical and cell biological properties of these previously highly elusive ...
Engelstoft, Maja S +3 more
openaire +4 more sources
Free Fatty Acid Receptors in Enteroendocrine Cells [PDF]
Endocrinology, 2018 Free fatty acid receptors (FFAs) are highly enriched in enteroendocrine cells providing pathways to link dietary fats and microbially generated short-chain fatty acids (SCFAs) to the secretion of a variety of gut hormones. FFA1 and FFA4 are receptors for long-chain fatty acids that have been linked to the elevation of plasma gut hormones after fat ...
Lu, Van B +2 more
openaire +6 more sources
BMC Gastroenterology, 2017 Background This study examined whether the densities of stem- and enteroendocrine cell progenitors are abnormal in the ileum of patients with irritable bowel syndrome (IBS), and whether any abnormalities in ileal enteroendocrine cells are correlated with
Magdy El-Salhy, Odd Helge Gilja
doaj +2 more sources
Microbial regulation of enteroendocrine cells
Med, 2021 There has been an enormous interest to investigate impact of gut microbiota on host physiology over the past decade. To further understand its role at organismal level, it is important to delineate host-microbiota interaction at tissue and cell level.
Arora, Tulika +3 more
openaire +4 more sources
Enteroendocrine cells in terminal ileal Crohn's disease
Journal of Crohn's and Colitis, 2012 Enteroendocrine cells sense gut luminal contents, and orchestrate digestive physiology whilst contributing to mucosal homeostasis and innate immunity. The terminal ileum is the key site of EEC expression but detailed assessment of their subtypes, lineage transcription factors and expression products has not been undertaken in terminal ileal Crohn's ...
Moran, Gordon +2 more
openaire +3 more sources