Results 61 to 70 of about 1,444 (144)

A Gnotobiotic Mouse Model for Studying the Effect of Human Gut Community Ecology on a Pathobiont, Bacteroides fragilis [PDF]

, 2015
OF THE DISSERTATION A Gnotobiotic Mouse Model for Studying the Effect of Human Gut Community Ecology on a Pathobiont, Bacteroides fragilis by Vitas Wagner Doctor of Philosophy in Biology and Biomedical Sciences Evolution, Ecology, and Population Biology ...
Wagner, Vitas
core   +1 more source

The Dysregulation of Polyamine Metabolism in Colorectal Cancer Is Associated with Overexpression of c-Myc and C/EBP β [PDF]

, 2016
Colorectal cancer is one of the most common cancers in the world. It is well known that the chronic inflammation can promote the progression of colorectal cancer (CRC).
Alexey A. Dmitriev, Anastasiya V. Lipatova, Anastasiya V. Snezhkina, Andrew R. Zaretsky, Andrey D. Kaprin, Anna V. Kudryavtseva, Asiya F. Sadritdinova, Boris Y. Alekseev, George S. Krasnov, Maria S. Fedorova, Nataliya V. Melnikova, Oleg A. Stepanov, Olga L. Kardymon   +12 more
core   +2 more sources

A highly conserved SusCD transporter determines the import and species-specific antagonism of Bacteroides ubiquitin homologues

Nature Communications
Efficient interbacterial competitions and diverse defensive strategies employed by various bacteria play a crucial role in acquiring a hold within a dense microbial community.
Ming Tong, Jinghua Xu, Weixun Li, Kun Jiang, Yan Yang, Zhe Chen, Xuyao Jiao, Xiangfeng Meng, Mingyu Wang, Jie Hong, Hongan Long, Shuang-Jiang Liu, Bentley Lim, Xiang Gao   +13 more
doaj   +1 more source

A review of the role of enterotoxigenic Bacteroides fragilis in the development of colorectal cancer

Basic & Clinical Cancer Research
Enterotoxigenic Bacteroides fragilis (ETBF) plays a significant role in the development and progression of colorectal cancer (CRC) through the production of Bacteroides fragilis toxin (BFT). This toxin activates Wnt, NF-κB, and STAT3 signaling pathways,
Abolfazl Jafari-Sales, Maryam Farahnaki-Sadabadi, Elham Nozohour-Leilabadi, Negin Yagoubi Azar, Maryam Safari, Mehrdad Pashazadeh   +5 more
doaj   +1 more source

Bacteroides Fragilis‐Derived Outer Membrane Vesicles Deliver MiR‐5119 and Alleviate Colitis by Targeting PD‐L1 to Inhibit GSDMD‐Mediated Neutrophil Extracellular Trap Formation

Advanced Science, Volume 12, Issue 35, September 18, 2025.
Bacteroides fragilis‐derived outer membrane vesicles deliver miR‐5119 and alleviate colitis by targeting PD‐L1 to inhibit GSDMD‐mediated neutrophil extracellular trap formation. Abstract Inflammatory bowel disease (IBD) results from a breakdown in the symbiotic relationship between the intestinal commensal microflora and the mucosal immune system.
Yi Yang, Lanmengxi Yang, Yilin Yang, Haiyi Deng, Shiyu Su, Yinxiao Xia, Jin Su, Yuheng Liu, Junwei Wu, Jing Zhang, Yao Liao, Lifu Wang   +11 more
wiley   +1 more source

Gastrointestinal Pathobionts in Pediatric Crohn’s Disease Patients

International Journal of Microbiology, 2018
Crohn’s disease (CD) is an inflammatory disease of the gastrointestinal tract, with a rising incidence worldwide, particularly in children. CD is thought to arise due to an immune response to environmental factors. The role of bacteria in CD has recently
Rachel V. Purcell, Nadeem O. Kaakoush, Hazel M. Mitchell, John F. Pearson, Jacqueline I. Keenan   +4 more
doaj   +1 more source

Cancer stem cells: Bridging microenvironmental interactions and clinical therapy

Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.
Cancer stem cells (CSCs) drive tumor progression through their dynamic self‐renewal capacity, epigenetic plasticity, and drug resistance. These cells interact bi‐directionally with the tumor ecosystem to promote immunosuppressive reprogramming and metastatic spread.
Huiling Wang, Junshu Li, Fei Du, Hongxin Deng   +3 more
wiley   +1 more source

Interaction Between Microbiota and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and New Therapeutic Opportunities

MedComm, Volume 6, Issue 7, July 2025.
This review systematically concludes the interaction between microbiota and immunity. We introduce six phyla: Bacteroidetes, Firmicutes, Actinobacteria, Proteobacteria, Fusobacteria, and Verrucomicrobia. We also elucidate molecular mechanisms, biological functions, diseases, and new therapeutic opportunities between microbiota and immunity. .
Jingjing Zeng, Zimeng He, Guoqing Wang, Yuxin Ma, Feng Zhang   +4 more
wiley   +1 more source

Photodynamic therapy of cancer‐associated infections

Photochemistry and Photobiology, Volume 101, Issue 4, Page 833-845, July/August 2025.
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley   +1 more source

Association between colorectal cancer and Fusobacterium nucleatum and Bacteroides fragilis bacteria in Iranian patients: a preliminary study

Infectious Agents and Cancer, 2021
Background and aim Recent studies have proposed that commensal bacteria might be involved in the development and progression of gastrointestinal disorders such as colorectal cancer (CRC).
Aref Shariati, Shabnam Razavi, Ehsanollah Ghaznavi-Rad, Behnaz Jahanbin, Abolfazl Akbari, Samira Norzaee, Davood Darban-Sarokhalil   +6 more
doaj   +1 more source