Results 31 to 40 of about 11,065 (134)

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

open access: yesAdvanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias   +23 more
wiley   +1 more source

Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells

open access: yesToxins, 2019
Clostridium perfringens enterotoxin (CPE) contributes to diarrhea and an often-lethal enterotoxemia. CPE action starts when it binds to claudin receptors, forming a small complex (90 kDa). Six small complexes then oligomerize to create prepores, followed
Iman Mehdizadeh Gohari   +4 more
doaj   +1 more source

Anti-inflammatory effects of animal plasma protein supplementation in mice undergoing simultaneous gut and lung inflammation

open access: yesFood and Agricultural Immunology, 2020
We aimed to determine whether dietary supplementation with spray-dried porcine plasma (SDP) is effective in mice exposed to a dual S. aureus enterotoxin B (SEB) and lipopolysaccharide (LPS) challenges inducing simultaneous inflammation in the gut and ...
L. Miró   +4 more
doaj   +1 more source

Detection of Staphylococcus aureus and enterotoxin genes from meat products by using conventional and modern identification methods [PDF]

open access: yesBenha Veterinary Medical Journal, 2019
One hundred meat product samples (minced meat, kofta, burger and sausage, 25 of each) were collected and examined for bacteriological evaluation and detection of Staphylococcus aureus by conventional bacteriological methods and by polymerase chain ...
Ahmed maarouf   +4 more
doaj   +1 more source

Characterization of Virulence Factors in Enterotoxin-Producing Staphylococcus aureus from Bulk Tank Milk

open access: yesAnimals, 2022
Staphylococcus aureus, a persistent mastitis-causing pathogen, produces various virulence factors, including enterotoxins. This study analyzed the genetic characteristics of bovine-mastitis-related virulence factors to evaluate the potential pathogenesis
Hye-Ri Jung, Young Ju Lee
doaj   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

open access: yesAdvanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun   +18 more
wiley   +1 more source

Purification and Characterization of Native and Vaccine Candidate Mutant Enterotoxigenic Escherichia coli Heat-Stable Toxins

open access: yesToxins, 2018
Enterotoxigenic Escherichia coli (ETEC), which secretes the heat-stable toxin (ST) is among the four most important enteropathogens that cause moderate-to-severe diarrhea in children in low- and middle-income countries.
Morten L. Govasli   +5 more
doaj   +1 more source

Molecular detection of enterotoxigenic Staphylococcus aureus in ready to eat beef products [PDF]

open access: yesBenha Veterinary Medical Journal, 2019
Ready to eat (RTE) meat products are considered a rapid way to animal protein intake which may be preferred by consumers due to its palatability and quality; unfortunately, cooked meat products may be loaded by many foodborne pathogens especially ...
Marionette Zaghloul   +4 more
doaj   +1 more source

Apoptosis-mediated inhibition of human T-cell acute lymphoblastic leukemia upon treatment with Staphylococus Aureus enterotoxin-superantigen

open access: yesFrontiers in Immunology, 2023
Patients with relapsed T cell acute lymphoblastic leukemia (T-ALL) have limited therapeutic options and poor prognosis. The finding of efficient strategies against this refractory neoplasm is a medical priority.
Alejandra Duarte   +4 more
doaj   +1 more source

Effects of Dietary Mannan Oligosaccharides on Growth, Disease Resistance, and Gut Microbiota in Zebrafish

open access: yesAnimal Research and One Health, EarlyView.
Supplementation with mannan oligosaccharides (MOS) enhances growth, disease resistance, antioxidant capacity, and gut microbiota diversity while suppressing inflammation, apoptosis, and strengthening intestinal barrier integrity in zebrafish challenged with LPS or DSS.
Zhiyuan Lu   +4 more
wiley   +1 more source

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