Results 71 to 80 of about 64,082 (215)

Influenza A Virus (H1N1) Infection Induces Ferroptosis to Promote Developmental Injury in Fetal Tissues

Cell Proliferation, EarlyView.
H1N1 infection during pregnancy specifically targets the fetal liver and lungs, triggering immune responses, tissue fibrosis and ferroptosis in parenchymal cells, ultimately leading to adverse pregnancy outcomes, offering insights into managing maternal H1N1 infections and their impact on fetal health.
Yuxi Jiang, Yao Shen, Qiongyin Zhang, Zi Liu, Yuzhen Liu, Jiaojiao Peng, Xuesong Yang, Feng Gao, Xiang‐Hong Ou, Qing‐Yuan Sun, Qiao Zhang, Guang Wang   +11 more
wiley   +1 more source

Whole Genome Sequencing of Enteroviruses Species A to D by High-Throughput Sequencing: Application for Viral Mixtures

Frontiers in Microbiology, 2018
Human enteroviruses (EV) consist of more than 100 serotypes classified within four species for enteroviruses (EV-A to -D) and three species for rhinoviruses, which have been implicated in a variety of human illnesses. Being able to simultaneously amplify
Marie-Line Joffret, Marie-Line Joffret, Marie-Line Joffret, Patsy M. Polston, Patsy M. Polston, Richter Razafindratsimandresy, Maël Bessaud, Maël Bessaud, Maël Bessaud, Jean-Michel Heraud, Francis Delpeyroux, Francis Delpeyroux, Francis Delpeyroux   +12 more
doaj   +1 more source

Sequencing of ‘untypable’ enteroviruses reveals two new types, EV-77 and EV-78, within human enterovirus type B and substitutions in the BC loop of the VP1 protein for known types

Journal of General Virology, 2003
The N-terminal part of VP1 was sequenced for 43 enterovirus isolates that could not initially be neutralized with LBM pools or in-house antisera. Most isolates were found to belong to human enterovirus type A (HEV-A) and HEV-B (18 isolates of each). All HEV-A isolates could be typed by sequencing, with CV (coxsackievirus)-A16 and EV (enterovirus)-71 ...
Norder, H., Bjerregaard, L., Magnius, L., Aymard, M., Chomel, Jj, Lina, B.   +5 more
openaire   +3 more sources

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, EarlyView.
The SARS‐CoV‐2 nucleocapsid (N) protein facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone. The Omicron BA.5 variant shows reduced chaperone activity compared to the Wuhan wild‐type protein. Although phosphorylation has no effect on wild‐type N, phosphomimetic modification of BA.5 N restores its RNA ...
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source

Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1 [PDF]

, 2019
Comprehensive knowledge of the host factors required for picornavirus infection would facilitate antiviral development.
Adamovich, Baggen, Bazzone, Bergelson, Berry, Bladt, Brandenburg, Carthy, Coyne, Coyne, Dodding, Donnelly, Edelman, Fernández-Puentes, Franz, Frischknecht, Fujimoto, Galisteo, Galletta, Glaser, Grøvdal, Hackett, Howlin, Huber, Innocenti, Jacobi, Jiang, Jones, Jose, Karlas, Keszei, Kim, König, Liu, Lupberger, Madshus, Madshus, Mahajan, Mahajan, Mahajan, Massaad, Melnick, Nguyen, Oppliger, Peterson, Porotto, Prieto-Echagüe, Prieto-Echagüe, Rohatgi, Rohatgi, Shen, Staring, Stradal, Teo, Wang, Winston, Wolf, Yamauchi, Yokoyama, Yokoyama, Zerbino   +60 more
core   +2 more sources

Impact of the BioFire FilmArray Meningitis‐Encephalitis Panel on Management of Suspected Paediatric Central Nervous System Infections: A Single‐Centre Retrospective Cohort Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Meningoencephalitis causes significant morbidity and mortality in children worldwide. Prompt diagnosis remains challenging, yet advances in molecular diagnostic technology have improved diagnostic performance. This study examined whether the introduction of the BioFire FilmArray meningitis/encephalitis (ME) multiplex panel impacted ...
Louisa Mary Churcher, Adam William Bartlett, Stella Pendle, Rob Slade, Phoebe C. M. Williams   +4 more
wiley   +1 more source

Human SCARB2-mediated entry and endocytosis of EV71. [PDF]

PLoS ONE, 2012
Enterovirus (EV) 71 infection is known to cause hand-foot-and-mouth disease (HFMD) and in severe cases, induces neurological disorders culminating in fatality.
Yi-Wen Lin, Hsiang-Yin Lin, Yueh-Liang Tsou, Ebenezer Chitra, Kuang-Nan Hsiao, Hsiao-Yun Shao, Chia-Chyi Liu, Charles Sia, Pele Chong, Yen-Hung Chow   +9 more
doaj   +1 more source

Rhinovirus detection using different PCR-based strategies [PDF]

, 2012
Human rhinoviruses (HRVs) are the major cause of the common cold. HRVs were recently reclassified into the Enterovirus genus (HEV) in the Picornaviridae family.
Bellei, Nancy Cristina Junqueira, Carraro, Emerson, Granato, Celso Francisco Hernandes, Perosa, Ana Helena Sitta, Silva, Ellen Ricci Monteiro da, Watanabe, Aripuanã Sakurada Aranha   +5 more
core   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Near-complete genome sequencing of swine vesicular disease virus using the Roche GS FLX sequencing platform. [PDF]

PLoS ONE, 2014
Swine vesicular disease virus (SVDV) is an enterovirus that is both genetically and antigenically closely related to human coxsackievirus B5 within the Picornaviridae family.
Sandra C Abel Nielsen, Christian A W Bruhn, Jose Alfredo Samaniego, Jemma Wadsworth, Nick J Knowles, M Thomas P Gilbert   +5 more
doaj   +1 more source