Results 11 to 20 of about 5,862 (206)

Muscle-Tendon-Enthesis Unit [PDF]

Seminars in Musculoskeletal Radiology, 2018
AbstractInjuries to the muscle-tendon-enthesis unit are common and a significant source of pain and loss of function. This article focuses on the important anatomical and biomechanical considerations for each component of the muscle-tendon-enthesis unit. We review normal and pathologic conditions affecting this unit, illustrating the imaging appearance
Tadros, Anthony S, Huang, Brady K, Pathria, Mini N   +2 more
openaire   +6 more sources

Assembly, maturation, and degradation of the supraspinatus enthesis [PDF]

Journal of Shoulder and Elbow Surgery, 2018
The development of the rotator cuff enthesis is still poorly understood. The processes in the early and late developmental steps are gradually elucidated, but it is still unclear how cell activities are coordinated during development and maturation of the structured enthesis.
Peter T. Jensen, Kate L. Lambertsen, Lars H. Frich   +2 more
openaire   +5 more sources

Single-cell RNA sequencing reveals cellular and molecular heterogeneity in fibrocartilaginous enthesis formation

eLife, 2023
The attachment site of the rotator cuff (RC) is a classic fibrocartilaginous enthesis, which is the junction between bone and tendon with typical characteristics of a fibrocartilage transition zone. Enthesis development has historically been studied with
Tao Zhang, Liyang Wan, Han Xiao, Linfeng Wang, Jianzhong Hu, Hongbin Lu   +5 more
doaj   +2 more sources

Enthesis Healing Is Dependent on Scaffold Interphase Morphology—Results from a Rodent Patellar Model

Cells, 2022
The use of multiphasic scaffolds to treat injured tendon-to-bone entheses has shown promising results in vitro. Here, we used two versions of a biphasic silk fibroin scaffold to treat an enthesis defect created in a rat patellar model in vivo.
Carlos J. Peniche Silva, Sebastian A. Müller, Nicholas Quirk, Patrina S. P. Poh, Carla Mayer, Antonella Motta, Claudio Migliaresi, Michael J. Coenen, Christopher H. Evans, Elizabeth R. Balmayor, Martijn van Griensven   +10 more
doaj   +2 more sources

Hedgehog signaling directs cell differentiation and plays a critical role in tendon enthesis healing

npj Regenerative Medicine
A high prevalence of rotator cuff tears presents a major clinical challenge. A better understanding of the molecular mechanisms underlying enthesis development and healing is needed for developing treatments.
Fei Fang, Matthew Casserly, Julia Robbins, Stavros Thomopoulos   +3 more
doaj   +2 more sources

Mineral Distributions at the Developing Tendon Enthesis [PDF]

PLoS ONE, 2012
Tendon attaches to bone across a functionally graded interface, "the enthesis". A gradient of mineral content is believed to play an important role for dissipation of stress concentrations at mature fibrocartilaginous interfaces. Surgical repair of injured tendon to bone often fails, suggesting that the enthesis does not regenerate in a healing setting.
Andrea G Schwartz, Jill D Pasteris, Guy M Genin, Tyrone L Daulton, Stavros Thomopoulos   +4 more
openaire   +5 more sources

The Correlation between the Elastic Modulus of the Achilles Tendon Enthesis and Bone Microstructure in the Calcaneal Crescent [PDF]

Tomography
Background: The calcaneal enthesis, an osseous footprint where the Achilles tendon seamlessly integrates with the bone, represents a complex interface crucial for effective force transmission.
Kenichiro Doi, Dina Moazamian, Behnam Namiranian, Sheronda Statum, Amir Masoud Afsahi, Takuaki Yamamoto, Karen Y. Cheng, Christine B. Chung, Saeed Jerban   +8 more
doaj   +2 more sources

MULTISCALE ENTHESIS MECHANICS

, 2015
Mechanical issues pertinent to multiscale mechanics of enthesis concentrating on state-of-the art knowledge are outlined. Coupling between nanoscale, microscale and macroscale effects is demonstrated.
Victor Birman, Guy Genin, Stavros Thomopoulos   +2 more
openaire   +3 more sources

Annexin A5 Involvement in Bone Overgrowth at the Enthesis [PDF]

Journal of Bone and Mineral Research, 2018
ABSTRACT   Little is known about the molecular mechanisms of enthesis formation in mature animals. Here, we report that annexin A5 (Anxa5) plays a critical role in the regulation of bone ridge outgrowth at the entheses.
Shimada, Akemi, Ideno, Hisashi, Arai, Yoshinori, Komatsu, Koichiro, Wada, Satoshi, Yamashita, Teruhito, Amizuka, Norio, Pöschl, Ernst, Brachvogel, Bent, Nakamura, Yoshiki, Nakashima, Kazuhisa, Mizukami, Hiroaki, Ezura, Yoichi, Nifuji, Akira   +13 more
openaire   +6 more sources

On the anatomy and histology of the pubovisceral muscle enthesis in women [PDF]

Neurourology and Urodynamics, 2011
AbstractAimsThe origin of the pubovisceral muscle (PVM) from the pubic bone is known to be at elevated risk for injury during difficult vaginal births. We examined the anatomy and histology of its enthesial origin to classify its type and see if it differs from appendicular entheses.MethodsParasagittal sections of the pubic bone, PVM enthesis ...
Kim, Jinyong, Ramanah, Rajeev, DeLancey, John O.L., Ashton‐Miller, James A.   +3 more
openaire   +5 more sources