Results 11 to 20 of about 3,843 (182)

Muscle-Tendon-Enthesis Unit [PDF]

Seminars in Musculoskeletal Radiology, 2018
AbstractInjuries to the muscle-tendon-enthesis unit are common and a significant source of pain and loss of function. This article focuses on the important anatomical and biomechanical considerations for each component of the muscle-tendon-enthesis unit. We review normal and pathologic conditions affecting this unit, illustrating the imaging appearance
Tadros, Anthony S, Huang, Brady K, Pathria, Mini N   +2 more
openaire   +4 more sources

Characterization of the distributions of collagen and PGs content in the decellularized book-shaped enthesis scaffolds by SR-FTIR

BMC Musculoskeletal Disorders, 2021
Background Bone-tendon interface (enthesis) plays a pivotal role in relaxing load transfer between otherwise structurally and functionally distinct tissue types.
Qiang Shi, Can Chen, Muzhi Li, Yang Chen, Yan Xu, Jianzhong Hu, Jun Liu, Hongbin Lu   +7 more
doaj   +1 more source

The Sound of Enthesis [PDF]

The Journal of Rheumatology, 2010
The enthesis, a 1-millimeter universe, is an area of great interest for the spondyloarthritis (SpA) research community. Our understanding of this critical anatomical area has dramatically improved over the past few years, but much remains to be learned.
Walter, Grassi, Marwin, Gutierrez, Emilio, Filippucci   +2 more
openaire   +2 more sources

Mesenchymal stem cell therapy regenerates the native bone-tendon junction after surgical repair in a degenerative rat model. [PDF]

PLoS ONE, 2010
BACKGROUND: The enthesis, which attaches the tendon to the bone, naturally disappears with aging, thus limiting joint mobility. Surgery is frequently needed but the clinical outcome is often poor due to the decreased natural healing capacity of the ...
Geoffroy Nourissat, Amadou Diop, Nathalie Maurel, Colette Salvat, Sylvie Dumont, Audrey Pigenet, Marjolaine Gosset, Xavier Houard, Francis Berenbaum   +8 more
doaj   +1 more source

Mechanical stimulation promotes enthesis injury repair by mobilizing Prrx1+ cells via ciliary TGF-β signaling

eLife, 2022
Proper mechanical stimulation can improve rotator cuff enthesis injury repair. However, the underlying mechanism of mechanical stimulation promoting injury repair is still unknown. In this study, we found that Prrx1+ cell was essential for murine rotator
Han Xiao, Tao Zhang, Changjun Li, Yong Cao, Linfeng Wang, Huabin Chen, Shengcan Li, Changbiao Guan, Jianzhong Hu, Di Chen, Can Chen, Hongbin Lu   +11 more
doaj   +1 more source

Pathogenesis of the Hallux Valgus: Enthesopathy of the Metatarsosesamoid Ligament

Foot & Ankle Orthopaedics, 2023
Category: Bunion; Basic Sciences/Biologics Introduction/Purpose: It is generally accepted that failure of the medial supporting soft tissue structure of the metatarsophalangeal joint plays an important role in the development of hallux valgus.
Hiroki Yabiku MD, Kotaro Higa MD
doaj   +1 more source

SARS-CoV-2 Infection Induces Psoriatic Arthritis Flares and Enthesis Resident Plasmacytoid Dendritic Cell Type-1 Interferon Inhibition by JAK Antagonism Offer Novel Spondyloarthritis Pathogenesis Insights

Frontiers in Immunology, 2021
ObjectiveBacterial and viral infectious triggers are linked to spondyloarthritis (SpA) including psoriatic arthritis (PsA) development, likely via dendritic cell activation.
Qiao Zhou, Qiao Zhou, Qiao Zhou, Jayakumar Vadakekolathu, Abdulla Watad, Kassem Sharif, Tobias Russell, Hannah Rowe, Almas Khan, Peter A. Millner, Peter Loughenbury, Abhay Rao, Robert Dunsmuir, Jake Timothy, Giovanni Damiani, Giovanni Damiani, Paolo D. M. Pigatto, Paolo D. M. Pigatto, Piergiorgio Malagoli, Giuseppe Banfi, Yasser M. El-Sherbiny, Charlie Bridgewood, Dennis McGonagle, Dennis McGonagle   +23 more
doaj   +1 more source

Anatomy and histomorphology of the flexor digitorum profundus enthesis: functional implications for tissue engineering and surgery

BMC Musculoskeletal Disorders, 2021
Background The enthesis possesses morphological adaptations across the soft-hard tissue junction which are not fully restored during surgical avulsion repairs.
Jeremy W. Mortimer, Hamad Alsaykhan, Subashan Vadibeler, Philippa A. Rust, Jennifer Z. Paxton   +4 more
doaj   +1 more source

Single-cell RNA sequencing reveals cellular and molecular heterogeneity in fibrocartilaginous enthesis formation

eLife, 2023
The attachment site of the rotator cuff (RC) is a classic fibrocartilaginous enthesis, which is the junction between bone and tendon with typical characteristics of a fibrocartilage transition zone. Enthesis development has historically been studied with
Tao Zhang, Liyang Wan, Han Xiao, Linfeng Wang, Jianzhong Hu, Hongbin Lu   +5 more
doaj   +1 more source

Enthesis Repair [PDF]

Journal of Bone and Joint Surgery, 2018
Abstract: On May 22, 2017, the National Institutes of Health (NIH)/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) hosted a roundtable on “Innovative Treatments for Enthesis Repair.” A summary of the roundtable discussion, as well as a list of the extramural participants, can be found at https://www.niams.nih.gov/
Kathleen A. Derwin, Leesa M. Galatz, Anthony Ratcliffe, Stavros Thomopoulos   +3 more
openaire   +2 more sources