Results 21 to 30 of about 3,843 (182)
Enthesis Healing Is Dependent on Scaffold Interphase Morphology—Results from a Rodent Patellar Model
Cells, 2022 The use of multiphasic scaffolds to treat injured tendon-to-bone entheses has shown promising results in vitro. Here, we used two versions of a biphasic silk fibroin scaffold to treat an enthesis defect created in a rat patellar model in vivo.
Carlos J. Peniche Silva +10 more
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Frontiers in Bioengineering and Biotechnology, 2021 The musculoskeletal system is composed by hard and soft tissue. These tissues are characterized by a wide range of mechanical properties that cause a progressive transition from one to the other.
Alberto Sensini +6 more
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eLife, 2021 The mechanical challenge of attaching elastic tendons to stiff bones is solved by the formation of a unique transitional tissue. Here, we show that murine tendon-to-bone attachment cells are bi-fated, activating a mixture of chondrocyte and tenocyte ...
Shiri Kult +15 more
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Tendon enthesis positional recruitment model
, 2021 A mathematical model was developed to describe the mechanics of the tendon enthesis across a range of joint orientations and geometries. This zip file contains all relevant code for the simulations in this paper. The MATLAB codes are as follow: 1) WORKING_V5_Postural_RecruitmentModel.m — runs the positional recruitment model with specified parameters 2)
Golman, Michael +2 more
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Cells, 2021 Objective: The spondylarthritides (SpA) are intimately linked to new bone formation and IL-17A and TNF pathways. We investigated spinal soft tissue and bone mesenchymal stem cell (MSC) responses to IL-17A and TNF, including their osteogenesis ...
Tobias Russell +12 more
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Bone & Joint Research, 2023 Aims: It has been established that mechanical stimulation benefits tendon-bone (T-B) healing, and macrophage phenotype can be regulated by mechanical cues; moreover, the interaction between macrophages and mesenchymal stem cells (MSCs) plays a ...
Linfeng Wang +7 more
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Apollo Medicine, 2015 Abstract Bone is a living tissue capable of changing its structure as the result of the stress to which it is subjected. It consists of cells, fibers and matrix. Calcification of extra cellular matrix makes it hard. The slight degree of elasticity in the bone is due to the presence of the organic fibers. The main function of the bone is protection of
Nitya Waghray +4 more
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Editorial Commentary: Kartogenin Promotes Wounded Enthesis Regeneration [PDF]
Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2018 Entheses are the insertion sites where tendons and ligaments attach to bone. Commonly, entheses are subject to overuse injuries, and tendon-to-bone healing is poor because the healing has occurred between 2 different tissues: hard tissue (bone) and soft tissue (tendon).
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Global Spine Journal, 2016 Background The pathogenesis of murine spondyloarthropathy (SpA) has been intimately linked to the presence of Interleukin(IL)-23 responsive, innate like lymphocytes at different anatomical regions including spinal enthesis. Human SpAs are associated with
Richard Cuthbert +5 more
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Scientific Reports, 2021 The enthesis allows the insertion of tendon into bone thanks to several remarkable strategies. This complex and clinically relevant location often features a thin layer of fibrocartilage sandwiched between tendon and bone to cope with a highly ...
Alexandra Tits +8 more
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